What are mouse ES cells?
What are mouse ES cells? Mouse embryonic stem cells (mESCs) are cells derived from the inner cell mass of the developing blastocyst1. They are able to self-renew indefinitely in vitro while preserving the developmental potential to reconstitute all embryonic lineages, ability that has been termed ‘naive’ pluripotency2. How transgenic mice are produced? Typically, transgenic mice […]