What is a CYP3A substrate?
What is a CYP3A substrate? CYP3A is responsible for the metabolism of more drugs than any other P450 enzyme. Other CYP3A substrates (dextromethorphan N-demethylation, nelfinavir, indinavir) have also been studied during pregnancy. N-demethylation of oral dextromethorphan was increased by 35–38% during pregnancy [27]. What does CYP3A4 substrate mean? Drugs metabolized by CYP3A4 are called CYP3A4 […]