What are the histological components of the liver?
What are the histological components of the liver?
The liver consists of the following major histological components: Parenchyma, which is represented by hepatocytes. Stroma, which is a continuation of the surrounding capsule of Glisson. It consists of connective tissue and contains the vessels.
What is the size and weight of the liver?
LIVER Normal Histology Rifat Mannan,MD Mount Sinai St.-Luke’s Roosevelt Hospital Center, New York 2. Anatomy • Second-largest organ of the body and the largest gland, weighing about 1-1.5 kg. • Comprises 2% of body weight.
What is the meaning of portal lobule in liver?
PORTAL LOBULE – It is defined as the part of the liver parenchyma that drains bile into the hepatic ductule present at the portal triad. -It is triangular in shape and can be visualised by drawing imaginary lines connecting the central veins of three adjacent liver lobules with portal triad at the centre. 26.
What is the functional unit of liver acinus?
A liver acinus functional unit is in the shape of an oval. The short axis is represented by a shared border between two adjacent lobules together with the portal canals.
What is the normal range of transaminases in liver disease?
On the other hand, chronic diseases of the liver such as alcoholic liver disease and chronic viral hepatitis are typically associated with smaller elevations of transaminases, in the 100–300 U/L range. Elevated ALT and AST with an AST/ALT ratio > 2:1 is classically associated with alcoholic hepatitis.
What are the signs and symptoms of liver disease?
Pathology of the Liver, Gallbladder, and Pancreas Abnormalities in laboratory tests are frequently the first or only sign of liver disease, and the pattern of abnormality is often suggestive of the underlying disease process. Gamma-glutamyltransferase (GGT) is particularly sensitive for liver disease.
What is the long axis of the liver acinus?
The long axis is an imaginary line between two adjacent central veins. Each liver acinus can be divided into three zones: Zone 1 – It is the one closest to the short axis, hence to the portal canals and supply of arterial blood. The hepatocytes in zone 1 receive the highest amount of oxygen.