What does lipemia index mean?
What does lipemia index mean?
Lipemia is a measure of serum transparency. High levels of blood lipids, mostly triglycerides, increase serum turbidity. The lipemia result is expressed in “number of plus signs,” ranging from negative to four pluses (++++).
What is increased in a lipemic sample?
In the lipemic sample, the proportion of lipid phase increases and can be up to 25%. Analytes that are not distributed in the lipid phase (i.e. electrolytes) are distributed in the aqueous part of the sample, which now accounts for only 75% of the sample.
Does lipemia affect calcium levels?
Conclusion: Lipemia causes clinically significant interferences for phosphorus, creatinine, total protein and calcium measurement and those interferences could be effectively removed by ultracentrifugation.
How do you prevent lipemic blood?
Please avoid food with high fat content before blood donation. If a blood donor consumes food with high fat content such as oily foods which are fried or deep fried before blood donation it can lead to a transient rise in the triglycerides or cholesterol levels resulting in lipemic blood.
How do you remove serum lipemia?
Conclusions: High-speed centrifugation (10,000×g for 15 minutes) can be used instead of ultracentrifugation to remove lipemia in serum/plasma samples. LipoClear and 1,1,2-trichlorotrifluoroethane are unsuitable as they interfere with the measurement of certain parameters.
What is slightly lipemic?
Lipemia is defined as visible turbidity in serum or plasma samples due to the presence of lipoprotein particles, especially chylomicrons. The most common cause of turbidity is a high concentration of triglycerides [1,2].
How can lipemia can be avoided?
One way to avoid grossly lipemic samples is to ask that patients fast for 12 hours before sample collection. If this is impractical, a mechanical-based means of clot detection should be available when samples are grossly lipemic.
How does lipemia affect creatinine?
Clinically significant interferences were found for phosphorus, creatinine, total protein and calcium. Conclusion: Lipemia causes clinically significant interferences for phosphorus, creatinine, total protein and calcium measurement and those interferences could be effectively removed by ultracentrifugation.
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