What is the function of DNA polymerase II?
What is the function of DNA polymerase II?
Eukaryotic RNA polymerase II (pol II) is a 12-subunit DNA-dependent RNA polymerase that is responsible for transcribing nuclear genes encoding messenger RNAs and several small nuclear RNAs (1).
What is RNA directed DNA polymerase?
An enzyme that synthesizes DNA on an RNA template. It is encoded by the pol gene of retroviruses and by certain retrovirus-like elements.
What is the function of DNA polymerase II quizlet?
What role does DNA polymerase play in copying DNA? DNA polymerase is an enzyme that joins indivisual nucleotides to produce a new strand of DNA. Replication in most prokaryotic cells starts from a single point and proceeds in two directions until the entire chromosome is copied.
Is DNA polymerase 2 found in eukaryotes?
DNA Polymerase II: Structure and Biochemical Functions Members of the family B polymerases are found throughout the Archaea; and, interestingly, the three replicative DNA polymerases of eukaryotic cells, as well as additional repair DNA polymerases, belong to family B.
What is the function of DNA polymerase 2 in prokaryotes?
Polymerase II is a DNA repair enzyme with a 3′ to 5′ exonuclease activity. Pol II is a family B polymerase and provides support to Pol III. When DNA acquires damage in the form of short gaps, which block Pol III activity, Pol II helps to remedy this problem by restarting DNA synthesis downstream of these gaps.
What is the difference between DNA polymerase 1 and DNA polymerase 2?
DNA polymerase 1, 2 and 3 are prokaryotic DNA polymerases involved in DNA replication. Pol 1 catalyzes the repairing of DNA damages. Pol 2 catalyzes the fidelity and processivity of DNA replication. Pol 3 catalyzes the 5′ to 3′ DNA polymerization.
What is virion in virus?
virion, an entire virus particle, consisting of an outer protein shell called a capsid and an inner core of nucleic acid (either ribonucleic or deoxyribonucleic acid—RNA or DNA).
What does RNA polymerase do?
RNA polymerase is an enzyme that is responsible for copying a DNA sequence into an RNA sequence, duyring the process of transcription.
What is the role of DNA polymerase III?
The main function of the third polymerase, Pol III, is duplication of the chromosomal DNA, while other DNA polymerases are involved mostly in DNA repair and translesion DNA synthesis. Together with a DNA helicase and a primase, Pol III HE participates in the replicative apparatus that acts at the replication fork.
How does RNA polymerase differ from DNA polymerase?
The main difference between DNA and RNA polymerase is that DNA polymerase produces a double-stranded DNA molecule during polymerization whereas RNA polymerase produces a single-stranded RNA molecule during transcription.
Where is RNA polymerase 2 found?
the nucleus
RNA polymerase II (RNAP II and Pol II) is a multiprotein complex that transcribes DNA into precursors of messenger RNA (mRNA) and most small nuclear RNA (snRNA) and microRNA. It is one of the three RNAP enzymes found in the nucleus of eukaryotic cells.
Where is RNA polymerase II synthesized?
nucleus
RNA polymerase II is located in the nucleus and synthesizes all protein-coding nuclear pre-mRNAs.