What is Porto portal fibrosis?

What is Porto portal fibrosis?

It occurs after centrolobular necrosis and produces new vascular connections between portal fields and central veins which may lead to cirrhosis. It is the most severe form of bridging necrosis and fibrosis and is most of the times associated with porto-portal fibrosis.

What is portal fibrosis of the liver?

Chronic diseases of the liver can lead to development of liver cirrhosis, characterized by formation of fibrotic septa which can be portal-portal in the case of the chronic biliary damage or portal-central in the case of the chronic viral hepatitis.

How is NCPF diagnosed?

The diagnosis of NCPF is mainly clinical – presentation with features of PHT without any evidence of liver dysfunction (rules out cirrhosis) and demonstration of patent hepatic (rules out Budd Chiari syndrome) and portal vein (rules out extra hepatic portal venous occlusion).

What is extrahepatic portal vein?

Extrahepatic portal vein obstruction is a vascular disorder of liver, which results in obstruction and cavernomatous transformation of portal vein with or without the involvement of intrahepatic portal vein, splenic vein, or superior mesenteric vein.

How long does it take for fibrosis to turn into cirrhosis?

In the majority of patients, progression to cirrhosis occurs after an interval of 15–20 years. Major clinical complications of cirrhosis include ascites, renal failure, hepatic encephalopathy, and variceal bleeding.

Is bridging fibrosis the same as cirrhosis?

Introduction: Advanced stage 3 fibrosis and bridging fibrosis is clinically considered early cirrhosis and followed as cirrhosis for the surveillance of varices and hepatocellular carcinoma (HCC).

What is the difference between liver fibrosis and liver cirrhosis?

Liver fibrosis occurs when the healthy tissue of your liver becomes scarred and therefore cannot work as well. Fibrosis is the first stage of liver scarring. Later, if more of the liver becomes scarred, it’s known as liver cirrhosis.

What is full form NCPF?

The full form of NCPF is National Curricular and Pedagogical Framework. The Early Childhood Care and Education policy ensures that every child is appreciated, accepted, feels safe and comfortable and develops a positive sense of self.

What is Ehpvo?

Extrahepatic portal venous obstruction (EHPVO) is the commonest cause of portal hypertension and variceal bleeding in children.

What causes portal vein hypertension?

The most common cause of portal hypertension is cirrhosis, or scarring of the liver. Cirrhosis results from the healing of a liver injury caused by hepatitis, alcohol abuse or other causes of liver damage. In cirrhosis, the scar tissue blocks the flow of blood through the liver and slows its processing functions.

How is Ehpvo diagnosed?

Pediatric EHPVO is idiopathic in most of the cases. Digestive hemorrhage and/or hypersplenism are the main symptoms. Doppler ultrasound is a non-invasive technique with a high degree of accuracy for the diagnosis. Morbidity is related to variceal bleeding, recurrent thrombosis, portal biliopathy and hypersplenism.