What does reducing substance in urine mean?
What does reducing substance in urine mean?
Urine reducing substances is a screening test for inborn errors of carbohydrate metabolism. Positive results can be followed up by sugar chromatography.
How is urine tested for reducing substances?
This test is usually run as a reflex test; only if the dipstick glucose is negative does the test ‘reflex’ to the reducing test. A negative dipstick glucose assay and a positive reducing test suggest that some substance other than glucose is present in the urine.
What reducing sugar is usually tested in urinalysis?
Although glucose is the sugar most commonly tested for in urine, normal human urine can contain small amounts of galactose, lactose, fructose, xylose, and other pentoses. Galactosuria, an abnormal amount of galactose in the urine, occurs in infants with a congenital metabolic defect.
How do you read urine lab results?
Normal values are as follows:
- Color – Yellow (light/pale to dark/deep amber)
- Clarity/turbidity – Clear or cloudy.
- pH – 4.5-8.
- Specific gravity – 1.005-1.025.
- Glucose – ≤130 mg/d.
- Ketones – None.
- Nitrites – Negative.
- Leukocyte esterase – Negative.
What is meant by reducing substances?
1. Definition. Reducing substances comprise all the sugars exhibiting ketonic and aldehydic functions and are determined by their reducing action on an alkaline solution of a copper salt.
What is the reason for performing tests for urinary reducing substances on all newborns?
It is used as a screening test for inborn errors of carbohydrate metabolism. Although the test has poor specificity and most states perform mandatory newborn screening for the common genetic defects, most clinical laboratories still perform this as a reflex test on all pediatric urine samples.
What is a reducing substance test?
Reducing substances are not normally present in urine and faeces. This test will detect the presence of reducing sugars, eg glucose, lactose, maltose, fructose and galactose. The test is normally carried out on children who fail to thrive and who could be lactose intolerant.
What are reducing substances?
Reducing substances comprise all the sugars exhibiting ketonic and aldehydic functions and are determined by their reducing action on an alkaline solution of a copper salt.
What does ketone bodies in urine indicate?
If your cells don’t get enough glucose, your body burns fat for energy instead. This produces a substance called ketones, which can show up in your blood and urine. High ketone levels in urine may indicate diabetic ketoacidosis (DKA), a complication of diabetes that can lead to a coma or even death.
What is considered a high WBC in urine?
You’re bound to have a few WBCs in your urine even when you’re healthy, but if a urine test identifies levels above 5 wbc/hpf, it’s likely you have an infection. If bacteria are detected, your doctor may perform a urine culture to diagnose the type of bacterial infection you have.
How many RBC in urine is normal?
A normal result is 4 red blood cells per high power field (RBC/HPF) or less when the sample is examined under a microscope. The example above is a common measurement for a result of this test.
What does a reducing substances stool test mean?
What is a stool reducing substances test? Stool (or faecal) reducing substances is a stool sample test used to diagnose lactose intolerance (and some rare metabolic abnormalities). Lactose intolerance can be caused by a prolonged or severe episode of viral gastroenteritis.
