How is nitroglycerin administered IV?
How is nitroglycerin administered IV?
Intravenous Administration Dilute nitroglycerin in 5% Dextrose Injection or 0.9% Sodium Chloride Injection to a final concentration of 200 to 400 mcg/mL depending on patient’s fluid status. A common dilution is 50 mg in 250 mL of 5% Dextrose Injection or 0.9% Sodium Chloride Injection.
Why is nitroglycerin given IV?
Nitroglycerin injection is used to treat hypertension (high blood pressure) during surgery or to control congestive heart failure in patients who have had a heart attack. It may also be used to produce hypotension (low blood pressure) during surgery.
What do you need to monitor when administering nitroglycerin IV?
Patient monitoring and titration of nitroglycerin drip A. Patient should have continuous cardiac rhythm monitoring and frequent blood pressure monitoring. Blood pressure should be rechecked after each dosing change.
How long is nitroglycerin IV stable?
The concentration of NTG in the i.v. solutions was determined spectrophotometrically. Nitroglycerin was found to be stable for at least 70 days when stored in glass containers, regardless of source, diluent (5% dextrose in water or normal saline) and storage temperature.
When do you give nitroglycerin IV?
When is nitroglycerin contraindicated?
Nitroglycerin is contraindicated in patients that have reported allergic symptoms to the medication. [18] Known history of increased intracranial pressure, severe anemia, right-sided myocardial infarction, or hypersensitivity to nitroglycerin are contraindications to nitroglycerin therapy.
What is the purpose of nitroglycerin?
Nitroglycerin is a vasodilator, a medicine that opens blood vessels to improve blood flow. It is used to treat angina symptoms, such as chest pain or pressure, that happens when there is not enough blood flowing to the heart.
Why nitroglycerin is given sublingually?
Nitrates. Glyceryl trinitrate (or nitroglycerin) undergoes extensive hepatic presystemic metabolism when given orally, and is therefore usually given by the sublingual route, by which it is well absorbed and rapidly taken up into the circulation.
What are the contraindications for nitroglycerin?
What is nitroglycerin tubing?
Nitroglycerin readily migrates into many plastics, including the polyvinyl chloride (PVC) plastics commonly used for intravenous administration sets. Nitroglycerin absorption by PVC tubing is increased when the tubing is long, the flow rates are low, and the nitroglycerin concentration of the solution is high.
When should you not give nitroglycerin?
ABSOLUTE: Discontinue nitroglycerin administration or do not administer nitroglycerin to patients who: Have a known sensitivity to nitrate medications. Have taken erectile dysfunction medications within the past 24 hours, such as Viagra, Cialis, Levitra, Stendra, Staxyn, sildenafil, avanafil, tadalafil or vardenafil.
Which of the following is a contraindication for nitroglycerin IV?
What is nitroglycerin IV used for?
Nitroglycerin injection is sometimes used to treat angina (chest pain) in patients who have been treated with other medicines that did not work well. Nitroglycerin belongs to the group of medicines called nitrates. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its work load.
What is the maximum dose of nitroglycerin?
Nitroglycerin Sublingual treatment for angina. Doctor: The recommended sublingual dose of Nitroglycerin is 0.2-0.6 mg every 5 minutes for maximum of 3 doses in 15 minutes, for the treatment of angina pectoris. It may also be used as a preventative therapy, 5-10 minutes prior to activities which may provoke an angina attack.
What is the formula for nitroglycerin?
Nitroglycerin, with the molecular formula C 3 H 5 (ONO 2) 3, has a high nitrogen content (18.5 percent) and contains sufficient oxygen atoms to oxidize the carbon and hydrogen atoms while nitrogen is being liberated, so that it is one of the most powerful explosives known.
