For what diseases could ATCC provide cells that could be used in research?
For what diseases could ATCC provide cells that could be used in research?
ATCC offers a wide variety of cancer cell lines for use in research related to cancer genetics, early detection methods, and effective treatment of disease. ATCC has the tools you need to test your clinical laboratory assays, imaging techniques, and genomic analyses.
What does ATCC screen cell lines for?
ATCC human cells are invaluable for your public health research. Human cell lines are a critical biological resource. These in vitro models of human biology are used in biomedical research, toxicology studies, bioindustry, drug discovery, vaccine development, protein production, and a host of other applications.
Which benchmark cell line verification is recommended by ATCC?
The American National Standards Institute (ANSI) and the American Type Culture Collection (ATCC) provide a documentary standard (ASN-0002) for human cell lines based on the use of short tandem repeats (STR) entitled Authentication of Human Cell Lines: Standardization of STR Profiling.
What is ATCC stands for?
American Type Culture Collection
2The American Type Culture Collection. The American Type Culture Collection (ATCC) is a private, nonprofit organization dedicated to the acquisition, preservation, authentication, and distribution—the “APAD” activities—of diverse biological materials.
Where is ATCC?
Our newly expanded headquarters and bioproduction facility is located in Manassas, Virginia, near Washington DC, and our FDA-registered biorepository facility and research and development center is located in Gaithersburg, Maryland.
What is the most useful cell?
HEK293, or human embryonic kidney-derived epithelial cells, are arguably one of the most widely used cell lines in cell biology research. HEK293 is a rapidly dividing, robust line cell with a good reputation for post-translational modification of its heterologously expressed proteins.
What is Hep3B cell?
In addition, HepG2 is hepatitis B virus negative and non-tumorigenic, but Hep3B is hepatitis B virus positive and tumorigenic (Knowles et al.
Are ATCC cell lines authenticated?
Unlike other providers, we authenticate cell lines by comparing the STR profile of sample cell lines with the ATCC Human Cell STR Database.
How do you authenticate a cell phone line?
The main test for authenticating cell lines is short tandem repeat (STR) profiling, the analysis of microsatellite regions of DNA that have variable numbers of repeats and are located throughout the genome.
How do I choose a cell line?
The Do’s and Dont’s of Choosing a Cell Line
- Don’t Choose Simply Because It Is Used in the Literature.
- Do Consider If It Fits Your Biological Model.
- Do Consider the Experiments You Want to Perform.
- Table 1: Features of commonly used cell lines.
- Don’t Assume That All Cell Lines Have the Same Culturing Requirements.
What is the ATCC cell line?
ATCC offers a line of serum-free cryopreservation media that are ready-to-use. This cell line has a mutation in codon 13 of the ras proto-oncogene. This cell line was initiated in 1972 through explant culture of lung carcinomatous tissue. ATCC hybridomas are widely used to produce monoclonal antibodies.
What is ATCC’s product catalog?
ATCC has the world’s largest and most extensive product catalog of human and animal cell lines for research purposes. The cell biology collection includes more than 4,000 continuous cell lines available by species, tissue/disease types, and signaling pathways.
What is ATATCC cell biology development?
ATCC cell biology development efforts focus on delivering more relevant in vitro models and research tools, such as authenticated and characterized primary cells as well as immortalized, stem, and continuous cell lines; disease and cellular pathway-specific cell line panels with genomic metadata; and assay ready genomic DNA.
What is hmec-1 (crl-3243)?
CRL-3243, HMEC-1, has been well characterized and shown to retain many of the characteristics of endothelial cells. These immortalized cells, because they are a continously renewable source of human endothelial microvascular cells, can be used as a replacement for primary human dermal endothelial cells for many research studies.
