Does diabetes cause myocarditis?

Does diabetes cause myocarditis?

Type 1 and type 2 diabetic patients are at increased risk of cardiomyopathy and heart failure is a major cause of death for these patients. Cardiomyopathy in diabetes is associated with a cluster of features including decreased diastolic compliance, interstitial fibrosis and myocyte hypertrophy.

How is diabetic cardiomyopathy diagnosed?

Echocardiography-defined cardiac dysfunction or morphological abnormalities in patients with overt HF often provide confirmatory diagnosis of diabetic cardiomyopathy. In the absence of symptoms in overt HF, the American College of Cardiology/American Heart Association (ACC/AHA) recommend imaging diagnosis [87].

How does diabetes cause dilated cardiomyopathy?

Etiologically, four main causes are responsible for the development of heart failure in diabetic cardiomyopathy: microangiopathy and related endothelial dysfunction, autonomic neuropathy, metabolic alterations that include abnormal glucose use and increased fatty acid oxidation, generation and accumulation of free …

How is cardiomyopathy treated in diabetes?

Administration of beta-blockers, angiotensin converting enzyme inhibitors (ACEi)/angiotensin receptor blockers (ARB) are currently the standard treatment for chronic HF with or without diabetes.

What is diabetic cardiomyopathy?

Diabetic cardiomyopathy is defined as the presence of abnormal cardiac structure and performance in the absence of other cardiac risk factors, such coronary artery disease, hypertension, and significant valvular disease.

Can diabetes cause heart issues?

If you have diabetes, you’re twice as likely to have heart disease or a stroke than someone who doesn’t have diabetes—and at a younger age. The longer you have diabetes, the more likely you are to have heart disease.

How common is diabetic cardiomyopathy?

Conclusion: Diabetic cardiomyopathy is relatively common in the community with a prevalence of 1.1%. The morbidity and mortality of patients with diabetic cardiomyopathy is high.

What type of cardiomyopathy is associated with diabetes?

The prevalence of diabetic cardiomyopathy is increasing in parallel with the increase in diabetes mellitus. Diabetic cardiomyopathy is initially characterized by myocardial fibrosis, dysfunctional remodeling, and associated diastolic dysfunction, later by systolic dysfunction, and eventually by clinical heart failure.

Can type 2 diabetes affect your lungs?

Lung Function If you have type 2 diabetes, you tend to have 3% to 10% lower lung volumes than adults who do not have the disease. Generally, reduced lung function won’t interfere with your daily life. However, it could cause issues if you are obese, smoke, or have lung disease.

Can diabetes cause shortness of breath?

People who have diabetes can have a high blood glucose, which is called hyperglycemia, or too little glucose, which is called hypoglycemia. Similar to ketoacidosis, too much or too little glucose can affect lung function and cause people to feel short of breath.

What are the signs and symptoms of diabetic cardiomyopathy?

Also, the diabetic patient may show subtle signs of diabetic cardiomyopathy related to decreased left ventricular compliance or left ventricular hypertrophy or a combination of both. A prominent “a” wave can also be noted in the jugular venous pulse, and the cardiac apical impulse may be overactive or sustained throughout systole.

What is the long latent phase of diabetic cardiomyopathy?

One particularity of diabetic cardiomyopathy is the long latent phase, during which the disease progresses but is completely asymptomatic. In most cases, diabetic cardiomyopathy is detected with concomitant hypertension or coronary artery disease.

What are the autonomic innervations of the myocardium in diabetic cardiomyopathy?

The autonomic innervations of the myocardium in diabetic cardiomyopathy are altered and contribute to myocardial dysfunction. Unlike the brain, the peripheral nervous system does not benefit from a barrier protecting it from the circulating levels of glucose.

Who are the authors of diabetic cardiomyopathy?

Diabetic cardiomyopathy: Pathophysiology, theories and evidence to date Lavanya Athithan, Gaurav S Gulsin, Gerald P McCann, and Eylem Levelt Lavanya Athithan Department of Cardiovascular Sciences, University of Leicester and NIHR Leicester Cardiovascular Biomedical Research Centre, Glenfield Hospital, Leicester LE3 9QP, United Kingdom.