How is biotransformation related to bioaccumulation?

How is biotransformation related to bioaccumulation?

Abstract: Bioaccumulation and biotransformation are key toxicokinetic processes that modify toxicity of chemicals and sensitivity of organisms. Biotransformation dominated toxicokinetics and strongly affected internal concentrations of parent compounds and metabolites.

What do you mean by biotransformation of drugs?

Biotransformation means chemical alteration of chemicals such as nutrients, amino acids, toxins, and drugs in the body. It is also needed to render non-polar compounds polar so that they are not reabsorbed in renal tubules and are excreted.

What is difference between bioaccumulation and biomagnification?

1) What is the difference between bioaccumulation and biomagnification? Bioaccumulation refers to the accumulation of a toxic chemical in the tissue of a particular organism. Biomagnification refers to the increased concentration of a toxic chemical the higher an animal is on the food chain.

What is the process of biotransformation?

28.5. Biotransformation is the process by which substances that enter the body are changed from hydrophobic to hydrophilic molecules to facilitate elimination from the body. This process usually generates products with few or no toxicological effects.

What is the meaning of bioaccumulation?

Bioaccumulation is defined as the net accumulation of a contaminant in or on an organism from all sources including water, air, and diet (Newman and Unger, 2003).

How does biotransformation help the environment?

Biotransformation can be used as a cleanup method for both contaminated soil and water. In situ technologies do not require excavation of the contaminated soils and so may be less expensive, create less dust, and cause less release of contaminants than ex situ techniques.

What is the main purpose of biotransformation?

The major purpose of biotransformation is to chemically modify (metabolize) poorly excretable lipophilic compounds to more hydrophilic chemicals that are readily excreted in urine and/or bile. Without metabolism, lipophilic xenobiotics accumulate in biota, increasing the potential for toxicity.

What are the types of biotransformation?

Biotransformation is of two types: Enzymatic and Non-enzymatic. Enzymatic are further divided into Microsomal and Non-microsomal. Enzymatic Elimination is the biotransformation occurring due to various enzymes present in the body.

What is a difference between bioaccumulation and biomagnification also give an example of either one?

One difference is that bioaccumulation refers to the build-up of the chemical in the body of one organism while biomagnification refers to the build-up in multiple organisms. Biomagnification also requires movement up a food chain in order to occur, while bioaccumulation does not require that the animal be eaten.

What is the difference between bioaccumulation and biological magnification explain with any one example?

This is also referred to as biological magnification….Biomagnification and Bioaccumulation – Differences.

Biomagnification Bioaccumulation
Causes
An increase in the level as one moves higher in the food chain. An increase in the concentration of a substance inside an organism
Level of concentration of pollutant

What is another term for bioaccumulation?

In this page you can discover 4 synonyms, antonyms, idiomatic expressions, and related words for bioaccumulation, like: biomagnification, toxicant, organochlorine and allergenicity.

What is bioaccumulation explain the process of bioaccumulation?

Bioaccumulation is a process of accumulation of chemicals in an organism that takes place if the rate of intake exceeds the rate of excretion. Chemicals are introduced into the organism through exposure to the abiotic environment (soil, water, air) or as dietary intake (trophic transfer).

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