How many ATPS are produced from complete oxidation of palmitoyl-CoA?
How many ATPS are produced from complete oxidation of palmitoyl-CoA?
Considering an average production of 2.5 ATP/NADH and 1.5 ATP/FADH2 using the respiratory chain, you have 108 ATP molecules. However, 2 ATP molecules were consumed during the initial activation of Palmitate to Palmitoyl-CoA which is going to be oxidized in the mitochondria. So, net energy output = (108 – 2) = 106 ATP.
How does palmitoyl-CoA regulate fatty acid synthesis?
Allosteric control occurs as feedback inhibition by palmitoyl-CoA and activation by citrate. When there are high levels of palmitoyl-CoA, the final product of saturated fatty acid synthesis, it allosterically inactivates acetyl-CoA carboxylase to prevent a build-up of fatty acids in cells.
How many acetyl-CoA molecules are formed by complete β oxidation?
one acetyl-CoA
The long-chain acyl-CoA enters the fatty acid β-oxidation pathway, which results in the production of one acetyl-CoA from each cycle of fatty acid β-oxidation.
How is palmitoyl-CoA produced?
Palmitoyl CoA formed from palmitic acid, in the reaction below. The activation is catalyzed by palmitoyl-coenzyme A synthetase and the reaction proceeds through a two step mechanism, in which palmitoyl-AMP is an intermediate. The reaction is driven to completion by the exergonic hydrolysis of pyrophosphate.
How many ATP molecules are produced in the electron transport chain for each Fadh₂ used?
2.5 ATP/NADH and 1.5 ATP/FADH2 are produced in the electron transport chain.
How many carbons does palmitoyl-CoA have?
16 carbons
Last, the double bond is hydrogenated to yield a saturated intermediate. The process cycles with the addition of another malonyl-ACP to the growing chain until ultimately an intermediate with 16 carbons is produced (palmitoyl-CoA).
Which transfers malonyl group from CoA to ACP?
Explanation: Malonyl co-A ACP transferase transfers malonyl group from co-A to ACP. β-Ketoacyl ACP reductase reduces β-keto group to β-hydroxyl group.
