Is HSP a genetic disease?
Is HSP a genetic disease?
The hereditary spastic paraplegias (HSP) are a large group of inherited neurologic disorders that share the primary symptom of difficulty walking due to muscle weakness and muscle tightness (spasticity) in the legs. There are more than 80 different genetic types of HSP.
Can hereditary spastic paraplegia be cured?
There are no specific treatments to prevent, slow, or reverse HSP. Symptomatic treatments used for spasticity, such as muscle relaxants, are sometimes helpful. Regular physical therapy is important for muscle strength and to preserve range of motion. There are no specific treatments to prevent, slow, or reverse HSP.
Is spastic paraparesis fatal?
People with spastic paraplegia type 49 can develop recurrent episodes of severe weakness, hypotonia, and abnormal breathing, which can be life threatening.
What kind of doctor treats spasticity?
Physiatrists and rehabilitation specialists at the Department of Physical Medicine and Rehabilitation deliver specialized forms of treatment in order for you to regain function and control of your affected limb or limbs and reduce symptoms of spasticity.
What is Strumpell-Lorrain disease (HSP)?
Clinically, they present with lower limb spasticity and weakness. HSP, also called familial spastic paraplegia, was initially referred to as Strumpell-Lorrain disease, a name given for the two physicians who in the late 19th century independently described key features of spastic paraplegia.
Is Strümpell-Lorrain hereditary?
Despite this, we never thought about the possibility of a hereditary disease in the family, ‘says Philippe Grammont, founder and Vice-President of the French Association for Strümpell-Lorrain ( A.SL ). ‘The first symptoms of the disease appeared when I turned 35; problems while running and fatigue in the legs.
What is the French Strümpell-Lorrain Association?
At the time the first symptoms of the disease appeared for Philippe, hereditary spastic paraplegia was not well known, which created a feeling of isolation among patients. Philippe therefore decided to create the French Strümpell-Lorrain Association in 1992 to bring French patients together.
