What can mimic osteosarcoma?

What can mimic osteosarcoma?

Perhaps one of the most difficult diagnoses to miss is that of idiopathic myositis ossificans. In this condition, an individual may present with a rapidly growing painful mass. An X-ray will show rapid bone formation, which can look identical to a high-grade osteosarcoma.

What are the diagnostic key points of osteosarcoma?

A bone scan is a way to find out whether or not osteosarcoma may have spread to other bones beyond the place it started. Biopsy. A biopsy is the removal of a small amount of tissue for examination under a microscope. Other tests can suggest that a tumor is present, but only a biopsy can make a definitive diagnosis.

What are the variants of osteosarcoma?

The list of variants of osteosarcoma includes telangiectatic osteosarcoma, small cell osteosarcoma, high-grade surface osteosarcoma, secondary osteosarcoma, low-grade intraosseous osteosarcoma, parosteal osteosarcoma, and periosteal osteosarcoma.

Can osteosarcoma be mistaken for osteochondroma?

Parosteal osteosarcoma can be rarely confused with osteochondroma. A radiologic-pathologic correlation is essential. Cortex continuity is the most misleading imaging feature that may occur in parosteal osteosarcomas. A knowledge of this misleading pattern will help diagnose the lesion from the beginning.

Can bone mets be misdiagnosed?

Patients can present with diffuse bone pain or pathologic fractures leading to imaging studies that reveal both osteolytic and osteosclerotic lesions. Widespread metastatic disease may be initially misdiagnosed, such as in our patient, leading to medical errors.

Is Osteoblastoma benign?

Osteoblastoma is a rare benign bone tumor that accounts for about 1 percent of all primary bone tumors in the United States. It affects twice as many boys as girls. Similar to most primary benign bone tumors, osteoblastoma tends to form in the extremities, however it also often forms in the spine.

When is osteosarcoma diagnosed?

Osteosarcoma most often affects pre-teens and teens; the average age at diagnosis is 15. More than 75% of the cases are people less than 25 years old. This may be related to the “growth spurt” most teens experience at that age. Osteosarcoma can also occur in children and young adults.

What is conventional osteosarcoma?

Abstract. Conventional central osteosarcoma (CCO) is a high-grade intraosseous malignant bone tumor. The neoplastic cells produce osteoid or bone. A CCO is considered to be primary when the host bone is normal. A CCO is said to be secondary when the host bone is affected by other pathologic conditions.

Can a doctor tell the difference between a cyst and tumor?

In most cases, you can’t tell the difference between a cyst and a tumor just by looking at them. However, there are a few things you can watch for to see whether it’s more likely to be a cyst or a tumor. Keep in mind that these aren’t strict rules, so it’s best to have your doctor take a look.

Can osteosarcoma be misdiagnosed?

Osteosarcomas may also be misdiagnosed because other types of lesions may mimic their features. Florid reactive periostitis of the tubular bones of the hands and feel: a benign lesion which may simulate osteosarcoma.

What can mimic bone Mets?

We present two cases of mimics of bone metastasis: systemic mastocytosis and osteopoikilosis. These cases demonstrate clinical and radiological characteristics that would make a diagnosis of bone metastasis less likely, and highlight the need for an awareness of mimics of bone metastasis.

What are the diagnostic criteria for osteosarcoma of bone?

This paper refers only to the conventional central high grade primary osteosarcoma of bone, which represents about 90% of all cases of osteosarcoma. Diagnostic criteria To confirm diagnosis, a biopsy is always required. Biopsy material should be obtained by the use of either a large-core tissue biopsy or, preferably, by an open biopsy.

What are the regional lymph node metastases in osteosarcoma?

Regional lymph node metastases are rare in patients with osteosarcoma. Enlarged, tender regional lymph nodes are more suggestive of osteomyelitis, which should be considered in the differential diagnosis.

Can osteosarcoma be found in soft tissue?

More rarely osteosarcoma may arise in the soft tissue. World Health Organization (WHO) histologic classification of bone tumours divides osteosarcomas into central and surface tumours, and recognises a number of subtypes within each group [1].

What is the prevalence of osteosarcoma in the US?

Among primary malignant bone tumours, it ranks second in frequency after multiple myelomas. The incidence of classic osteosarcoma is 3 cases/million population/year. It represents 0.2% of all malignant tumours [3]. In about 75% of cases, patients with osteosarcoma are between 15–25 years of age.