What can you do for propofol infiltration?
What can you do for propofol infiltration?
Thus, we recommended use of a cool poultice for the 3 h to treat the extravasation injury by thiopental or propofol. Warm compresses must be avoided to treat the extravasation injury caused by these agents.
What is propofol extravasation?
Extravasation is an unintentional injection or leakage of fluid in the perivascular or subcutaneous space. Extravasation injury results from a combination of factors, including solution cytotoxicity, osmolality, vasoconstrictor properties, infusion pressure, regional anatomical peculiarities, and other patient factors.
What do you do with vancomycin infiltration?
Treatment includes stopping the infusion, delivery of a local antidote (if appropriate), and ice initially, followed by warm soaks or compresses. The extent of the injury will depend on how much vesicant fluid has come into contact with the tissue and how quickly the intervention was made.
What do you do for dobutamine infiltration?
Terbutaline, as mentioned previously, has been successful for the reversal of a mixed dopamine and dobutamine extravasation. 31 Phentolamine and nitroglycerin remain reasonable treatment options for dobutamine extravasations.
How do you manage extravasation?
At the first sign of extravasation, the following steps are recommended: (1) stop administration of IV fluids immediately, (2) disconnect the IV tube from the cannula, (3) aspirate any residual drug from the cannula, (4) administer a drug-specific antidote, and (5) notify the physician (Fig.
What is the difference between infiltration and extravasation?
The difference between an infiltration and extravasation is the type of medicine or fluid that is leaked. Infiltration – if the fluid is a non-vesicant (does not irritate tissue), it is called an infiltration. Extravasation – if the fluid is a vesicant (a fluid that irritates tissue), it is called an extravasation.
How is extravasation treated?
Treatment of a vesicant extravasation includes immediate cessation of infusion, aspiration of as much extravasated drug as possible through the still-intact catheter, and attempts for the aspiration of the extravasated agent in the surrounding tissue. This aspiration may help to limit the extent of tissue damage.
Can propofol go through a peripheral?
Utilize a Smart Pump and infuse through a central line if one is in place; otherwise, administer through a peripheral infusion line. F. Do not mix Propofol with other agents or co-administer with blood or plasma in the same I.V. catheter.
How is TPN extravasation treated?
The treatment of TPN extravasation should include early recognition of extravasation, with immediate discontinuation of the infusion [4,5,7]. Conservative measures such as elevation of the affected limb or the application of heat or cold have not shown any benefit [7,11-14].
What may indicate an extravasation injury?
Extravasation is the accidental leakage of certain medicines outside of the vein and into the surrounding tissues. Your child may have noticed pain, stinging, swelling or other changes to their skin at the site where they are given drugs or the nurse may have noticed that the drug was not flowing into the vein easily.
How do you aspirate extravasation?
If extravasation occurs, the injection should be stopped immediately and the IV tubing disconnected. Avoid applying pressure to the site, and do not flush the line. Leave the original catheter in place, and attempt to aspirate as much of the infiltrated drug as possible.
What is the antidote for extravasation?
These antidotes include isotonic (1/6 M) sodium thiosulfate for mechlorethamine (and optionally for cisplatin), hyaluronidase for the vinca alkaloids (and optionally for epipodophyllotoxins such as etoposide), and cooling with very topical DMSO and low dose hydrocortisone for the anthracyclines.
