What does metabolon do?

What does metabolon do?

Metabolon deciphers thousands of discrete chemical signals from genetic and non-genetic factors to reveal biological pathways. We make connections where other ‘omics cannot, and provide the definitive representation of the phenotype.

Where is metabolon located?

Founded in 2000 and based in Research Triangle Park, North Carolina, Metabolon has conducted more than 10,000 independent and collaborative studies, resulting in 2,000+ publications in leading peer-reviewed journals. For more information about our technology, products and services, please visit www.metabolon.com.

What is global metabolomics?

Metabolon’s Precision Metabolomics™ LC-MS global metabolomics platform provides a high-fidelity, reproducible analysis of the current-state of a biological system to help identify pharmacodynamic, efficacy and response biomarkers and reveal changes in key biological pathways.

How many metabolites are there?

Metabolite Statistics

Description Count
Total Number of Endogenous Metabolites 82,595
Total Number of Food Metabolites 32,368
Total Number of Microbial Metabolites 172
Total Number of Drug Metabolites 2,383

How many employees does metabolon have?

167
Company Description: Metabolon, Inc. is located in Morrisville, NC, United States and is part of the Scientific Research and Development Services Industry. Metabolon, Inc. has 167 total employees across all of its locations and generates $44.76 million in sales (USD).

Who uses metabolomics?

At present, metabolomics is applied to investigate several human diseases, to improve their diagnosis and prevention, and to design better therapeutic strategies. In addition, metabolomic studies are also being carried out in areas such as toxicology and pharmacology, crop breeding, and plant biotechnology.

What is unique about metabolomics?

The unique aspect of metabolomics among the ‘omic’ technologies (including genomics, epigenomics, transcriptomics and proteomics) is that measuring metabolites provides a retrospective and wide-ranging account of the biological processes that have occurred within an individual, which may be relevant to health and …

What is untargeted and targeted metabolomics?

Targeted metabolomics enables validation and absolute quantification of a chosen subset of metabolites (e.g., metabolites within a specific pathway). Global, untargeted metabolomics is hypothesis-generating. It is typically performed to collect and analyze all detectable metabolites in a sample.

What is the difference between targeted and non targeted metabolomics?

Targeted approaches require a priori knowledge of metabolites of interest and known compounds, are based on metabolite-specific signals, and do not achieve global coverage [17]. In contrast, non-targeted metabolomics approaches involve global profiling of the metabolome.

What is the first metabolite database?

One of the first dedicated metabolomics databases, the HMDB facilitates human metabolomics research, including the identification and characterization of human metabolites using NMR spectroscopy, GC-MS spectrometry and LC/MS spectrometry.

What do you mean by metabolize?

When you metabolize a substance, it is affected by chemical processes in your body so that, for example, it is broken down, absorbed, and used. [technical] Diabetics cannot metabolise glucose properly. [ VERB noun] COBUILD Advanced English Dictionary.

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