What is apixaban (apixaban)?
What is apixaban (apixaban)?
Apixaban is a novel oral anti-Xa antagonist, with demonstrated safety and efficacy as compared with agents such as warfarin in patients with atrial fibrillation and enoxaparin in patients undergoing orthopedic surgery.
What should I do if I run out of apixaban?
Be sure to refill your prescription before you run out of medication so that you will not miss any doses of apixaban. If you need to stop taking apixaban, your doctor may prescribe another anticoagulant (‘blood thinner’) to help prevent a blood clot from forming and causing you to have a stroke.
Why does apixaban take so long to stop bleeding?
Apixaban prevents blood from clotting normally, so it may take longer than usual for you to stop bleeding if you are cut or injured. This medication may also cause you to bruise or bleed more easily. Call your doctor right away if bleeding or bruising is unusual, severe, or cannot be controlled.
What are the interactions between apixaban and abametapir?
Interactions Drug Interaction Abametapir The serum concentration of Apixaban can Abatacept The metabolism of Apixaban can be increa Abciximab Apixaban may increase the anticoagulant
Apixaban is an oral anticoagulant and direct inhibitor of Factor Xa which is used to decrease the risk of venous thromboses, systemic embolization and stroke in patients with atrial fibrillation, and lower the risk of deep vein thrombosis and pulmonary embolus after knee or hip replacement surgery.
How do you take apixaban after surgery?
Apixaban comes as a tablet to take by mouth. It is usually taken with or without food twice a day. When apixaban is taken to prevent DVT and PE after hip or knee replacement surgery, the first dose should be taken at least 12 to 24 hours after surgery.
How long does apixaban take to work?
Apixaban is absorbed in the stomach and small intestine. For doses up to 10 mg, the absolute bioavailability is about 50%. For oral administration, absorption is not affected by the presence of food, and it takes about 3-4 hours to achieve maximum plasma concentrations.
Is apixaban safe for patients with atrial fibrillation (AF)?
Human Toxicity Excerpts. Apixaban is superior to warfarin in the prevention of thromboembolic complications in patients with AF, and there are case reports showing apixaban-associated resolution of LAA thrombus; however, the efficacy and safety of apixaban for the treatment of LAA thrombus remains unproven.
