What is aprepitant 125 mg used for?
What is aprepitant 125 mg used for?
Aprepitant comes as a capsule and as an oral suspension (liquid) to take by mouth. To prevent nausea and vomiting caused by cancer chemotherapy, aprepitant is usually taken once daily, with or without food, during the first few days of your cancer chemotherapy treatment.
What is aprepitant 80 mg used for?
Aprepitant is used with other medications to help prevent nausea and vomiting caused by cancer drug treatment (chemotherapy). Aprepitant works by blocking one of the body’s natural substances (substance P/neurokinin 1) that causes vomiting.
How is aprepitant administered?
[9] Aprepitant is available for oral suspension prepared by mixing the contents of one pouch of powder with 4.6 ml of water. The resulting suspension yields a 25 mg/ml strength for oral administration to pediatric patients or adults who cannot swallow capsules.
How do you mix Emends?
Pour the entire contents of the pouch into the 4.6 mL of water in the mixing cup and snap the lid shut. 7. Mix the EMEND suspension gently by swirling 20 times; then gently invert the mixing cup 5 times. To prevent foaming, do not shake the mixing cup.
What is aprepitant used for?
Aprepitant capsules and oral suspension are used in combination with other medicines to prevent the nausea and vomiting that may occur during cancer treatment (chemotherapy). Aprepitant capsules are also used to prevent nausea and vomiting that may occur after surgery.
Does aprepitant prolong QT?
The lack of QTc increase at this high dose of fosaprepitant and resulting aprepitant plasma exposures support the expectation that clinical doses of fosaprepitant or aprepitant will not be associated with significant QTc prolongation.
How do you take aprepitant capsules?
Take aprepitant capsules exactly as your doctor tells you to. You will be asked to take one 125 mg capsule one hour before your chemo treatment starts, and then one 80 mg capsule each morning for the following two days. Swallow the capsules whole – it may help to take your doses with a drink of water.
How do you take an aprepitant?
Aprepitant is an anti-sickness medicine. It is taken alongside other medicines to help stop sickness (nausea and vomiting) after chemotherapy. Take one 125 mg capsule an hour before chemotherapy, and then one 80 mg capsule each morning for the following two days.
What is the difference between fosaprepitant and aprepitant?
Fosaprepitant is a prodrug of aprepitant, and it is converted to aprepitant within 30 minutes when administered intravenously.
How long does aprepitant last?
Aprepitant is one of the effective antiemetic drugs that usually used for a period of 3 days for prevention of anthracycline/cyclophosphamide (AC) induced nausea and vomiting.
Can you open aprepitant capsules?
The first dose of aprepitant is usually given 30 to 60 minutes before treatment with chemotherapy. Follow your doctor’s dosing instructions very carefully. Aprepitant oral can be taken with or without food. Swallow the capsule whole and do not crush, chew, break, or open it.
Who manufactures aprepitant?
Princeton, New Jersey, January 4, 2017– Sandoz today announced the U.S. market introduction of aprepitant capsules, 40mg, 80mg, and 125mg, a generic version of Emend®1 by Merck Sharp & Dohme Corp.
