What is Excenel used for in calves?

What is Excenel used for in calves?

EXCENEL® RTU EZ (ceftiofur hydrochloride) Sterile Suspension is an efficacious anti-infective approved by the FDA for the treatment of acute postpartum metritis, bovine respiratory disease (BRD) and foot rot.

How do you give Excenel?

— For acute post-partum metritis: administer by intramuscular or subcu- taneous administration at the dosage of 1.0 mg ceftiofur equivalents/lb (2.2 mg/kg) BW (2 mL sterile suspension per 100 lb BW). Administer at 24 h intervals for five consecutive days. Do not inject more than 15 mL per injection site.

What is ceftiofur used for?

Ceftiofur hydrochloride is used in cattle and pigs for treatment and control of infections caused by susceptible pathogens. It is registered for treatment of respiratory disease in cattle caused by Mannheimia, P. multocida, and H. somni (formerly H.

What is Excenel used for in dogs?

EXCENEL RTU is indicated for treatment of: Acute postpartum metritis (uterine infection) caused by organisms susceptible to ceftiofur. Bovine respiratory disease (pneumonia, shipping fever, BRD) due to Mannheimia spp. (Pasteurella haemolytica), Pasteurella multocida and Haemophilus somnus.

How long does Excenel last?

Excenel RTU EZ Sterile Suspension Dosage And Administration Treatment should be repeated at 24 hour intervals for a total of three consecutive days.

What is ceftiofur sodium?

Ceftiofur Sodium is the sodium salt form of ceftiofur, a semisynthetic, beta-lactamase-stable, broad-spectrum, third-generation cephalosporin with antibacterial activity. Ceftiofur binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall.

What is Excenel RTU EZ used for?

EXCENEL RTU EZ Sterile Suspension is indicated for treatment/control of swine bacterial respiratory disease (swine bacterial pneumonia) associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Salmonella Choleraesuis and Streptococcus suis. DOSAGE AND ADMINISTRATION Shake well before using.

What kind of antibiotic is ceftiofur?

Ceftiofur is a broad-spectrum antibiotic of the cephalosporin group and is indicated for the treatment of respiratory disease in cattle. It is rapidly metabolized to desfuroylcetftiofur, which accounts for most of its antimicrobial activity.

What is Excenel used for in swine?

Swine: EXCENEL RTU EZ Sterile Suspension is indicated for treatment/control of swine bacterial respiratory disease (swine bacterial pneumonia) associated with Actinobacillus (Haemophilus) pleuropneumoniae, Pasteurella multocida, Salmonella Choleraesuis and Streptococcus suis.

What is Excenel used for in horses?

Excenel Sterile Powder Indications Horses: For treatment of respiratory infections in horses associated with Streptococcus zooepidemicus. Swine: For treatment of swine bacterial respiratory disease (swine bacterial pneumonia) associated with Actinobacillus pleuropneumoniae and Pasteurella multocida.

Is ceftiofur used in humans?

Ceftiofur is a third-generation cephalosporin. Cephalosporin antibiotics are also used in human medicine, and there are a total of four generations of cephalosporins.

Is ceftiofur safe for dogs?

Dogs: Ceftiofur sodium was well tolerated at the therapeutic dose and is safe for the treatment of urinary tract infections in dogs. In clinical studies, ceftiofur was well tolerated by dogs at the recommended level (2.0 mg/kg) for 5 – 14 days.

How many mg of ceftiofur are in a 50 ml suspension?

Each mL of this ready-to-use sterile suspension contains ceftiofur hydrochloride equivalent to 50 mg ceftiofur, 2.50 mg polyoxyethylene sorbitan monooleate (polysorbate 80), 6.5 mg water for injection in a caprylic/capric triglyceride suspension. Figure 1. Structure:

Is ceftiofur a bactericidal cephalosporin?

Like other cephalosporins, ceftiofur is bactericidal, in vitro, resulting from inhibition of cell wall synthesis.

What are the effects of ceftiofur in cattle?

The effects of ceftiofur on cattle and swine reproductive performance, pregnancy and lactation have not been determined. Intramuscular and subcutaneous injection in cattle and intramuscular injection in swine can cause a transient local tissue reaction that may result in trim loss of edible tissue at slaughter.

What is the primary metabolite of ceftiofur?

Ceftiofur administered as either ceftiofur sodium or ceftiofur hydrochloride is metabolized rapidly to desfuroylceftiofur, the primary metabolite.