What is the difference between apical and basal tissue layers?
What is the difference between apical and basal tissue layers?
The apical faces external environment or lumen of a tube where it is often involved in absorption or secretion. The basal mediates attachment to underlying tissue or surface via integrins.
Where is the apical surface of the skin?
The apical surface faces the lumen (inside of a hollow organ) while the basal or basolateral surface is adjacent to the underlying tissue. In many epithelia, the apical surface is specialized.
What is the apical surface of a cell?
The apical surface of epithelial cells, which lines the lumen of sac- and tube-shaped organs and the inner surfaces of the body cavities, forms the interface between the extracellular milieu and underlying tissues.
What are apical and basolateral domains?
To accomplish this, epithelial cells generate molecularly distinct domains along their plasma membranes: an apical domain that is exposed to the outside, a basolateral domain that contacts the interior, and, in between, an adhesion complex that holds the cell sheet together.
Which epithelial cells have a basal lamina?
The vascular basal lamina is a specialized form of ECM assembled by pericytes and endothelial cells. Lying between the pericytes and endothelial cells, and also overlying the pericytes, the basal lamina provides an additional means of interaction between the two cell types (Wagenseil and Mecham, 2009).
Where the apical basal and lateral surfaces of an epithelial cell are located?
All epithelial cells are polarized with the apical surface facing the lumen or external environment and the basal surface facing the basement membrane.
What is a basal surface?
In histology, the basal surface is the bottom edge of the cell or tissue adjacent to the basement membrane. The epithelial tissue acts as a covering. It lines cavities in the body and the surfaces of structures.
What is basal lamina?
Basal lamina are extracellular structures found closely apposed to the plasma membrane on the basal surface of epithelial and endothelial cells and surround muscle and fat tissues.
What does apical modification mean?
1- Apical (Surface or luminal) modifications: It is specialized to carry out functions that occur at these interfaces, including secretion, absorption, and movement of luminal contents. ▪ Cilia: are membrane-covered extensions of the entire apical surface.
