What medications are GnRH agonists?

What medications are GnRH agonists?

GnRH agonists (sold under the brand names Lupron, Zoladex, Trelstar, Viadur, Vantas, Eligard and Synarel – see Table below) are drugs that lower male hormones, which has the effect of shrinking prostate tumors or slowing the growth of prostate cancer. This therapy is known as Androgen Deprivation Therapy or ADT.

Why is GnRH agonist used for Superovulation?

The major advantages of GnRH antagonists use in superovulation include a gentler and more patient-friendly stimulation cycle with less hypoestrogenic side effects, with the potential to lower the risk of ovarian hyperstimulation and enhanced embryo growth.

Is Lupron a GnRH antagonist?

The commercial names and year of approval in the United States of the currently available forms of GnRH agonists and antagonists are: leuprolide, also called leuprorelin (Lupron: 1985), goserelin (Zoladex: 1989), histrelin (Supprelin, Vantas: 1991 and 2004), triptorelin (Trelstar: 2000), and degarelix (Firmagon: 2008).

Is danazol a GnRH agonist?

It was approved by the U.S. Food and Drug Administration (FDA) as the first drug to specifically treat endometriosis, but its role as a treatment for endometriosis has been largely replaced by the gonadotropin-releasing hormone (GnRH) agonists. Danazol has antigonadotropic and anti-estrogenic activities.

When are GnRH agonists used?

GnRH agonists are a group of drugs that have been used to treat women with endometriosis for over 20 years [1]. They are modified versions of a naturally occurring hormone known as gonadotropin releasing hormone, which helps to control the menstrual cycle.

Is Lupron an agonist or antagonist?

Lupron, a GnRH agonist, is one of the best known and most hated of IVF treatment injectable fertility drugs. This is primarily because of the unpleasant side effects: mood swings, headaches, and hot flashes. GnRH agonists like Lupron are primarily used for the treatment of endometriosis and fibroids.

What does a GnRH agonist do?

Gonadotropin releasing hormone agonists (GnRH) are a type of medication that suppresses ovulation by stopping the production of estrogen and progesterone. In order for this axis to function properly and result in ovulation, GnRH has to be released in a pulsatile fashion.

What does super ovulated mean?

Superovulation, also known as controlled ovarian hyperstimulation, is the process of inducing a woman to release more than one egg in a month.

Is Lupron a gonadotropin?

Leuprolide injection (Lupron Depot) is also used with other medication to treat anemia (a lower than normal number of red blood cells) caused by uterine fibroids (noncancerous growths in the uterus). Leuprolide injection is in a class of medications called gonadotropin-releasing hormone (GnRH) agonists.

Is danazol an anabolic steroid?

Danazol has a complex mechanism of action, and is characterized as a weak androgen and anabolic steroid, a weak progestogen, a weak antigonadotropin, a weak steroidogenesis inhibitor, and a functional antiestrogen.

What company makes danazol?

Learn more about Danazol | Lannett Company.

What is the difference between GnRH agonist and antagonist?

GnRH antagonists are more complex than agonists, and act through a completely different mechanism to inhibit gonadotropin secretion. GnRH antagonists bind competitively to GnRH receptors, preventing the action of endogenous GnRH pulses on the pituitary.