What is a normal thyroglobulin count?

What is a normal thyroglobulin count?

The normal range for thyroglobulin is: 1.40 – 29.2 ng/mL (μg/L) for men. 1.50 – 38.5 ng/mL for women.

How do you prepare for a thyroglobulin test?

Usually, no preparation is required before the thyroglobulin test. However, at certain times, depending on the method of test, some dietary supplements such as multivitamins should not be taken at least 12 hours before the test is done to avoid any kind of interference in the test.

What is thyroglobulin LCMS?

Thyroglobulin, LC/MS/MS – Measurement of thyroglobulin (Tg) is useful in the detection of residual or recurrent thyroid cancer. Many individuals develop auto-antibodies to Tg (Tg Ab) and the presence of Tg Ab interferes with the measurement of immunoassay Tg.

What is considered a high thyroglobulin level?

If your thyroglobulin range is “detectable” (this means it is – 5 ug/L or above), there is likely some normal thyroid tissue or cancerous tissue found. If your thyroglobulin range rises with time, and your TSH does not rise, there is likely some thyroid cancer which is growing.

How long does it take to get thyroglobulin test results?

Test Includes Thyroglobulin antibody (TgAb) testing is performed on all samples. If TgAb is negative, serum thyroglobulin is measured by a sensitive IMA with a relatively rapid turnaround time, generally two to three days. If TgAb is positive, serum thyroglobulin is measured by an RIA method.

How is thyroglobulin test done?

What happens during a thyroglobulin test? A health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out.

What if my thyroglobulin is high?

Your thyroglobulin levels are high and/or have increased over time. This may mean thyroid cancer cells are growing, and/or cancer is starting to spread. Little or no thyroglobulin was found. This may mean that your cancer treatment has worked to remove all thyroid cells from your body.

What causes high thyroglobulin?

Certain factors, such as gene defects, virus infection, iodine intake, stress or destruction of thyroid follicles caused by thyroid nodules (such as patients in high Tg group in the present study) and cancer, can lead to a raise of Tg level (30, 41, 42).

What causes elevated thyroglobulin?

Is there a hook effect for the access thyroglobulin assay?

The Access Thyroglobulin assay does not demonstrate any “hook” effect for concentrations up to 40,000 ng/mL. The Access Thyroglobulin Antibody does not demonstrate any “hook” effect up to approximately 50,000 IU/mL. For samples that are Tg antibody positive, Tg will be measured using an RIA method,which is less prone to Tg antibody interference.

How do you test for thyroglobulin antibodies?

Thyroglobulin antibody (TgAb) testing is performed on all samples. If TgAb is negative, serum thyroglobulin is measured by a sensitive IMA with a relatively rapid turnaround time, generally two to three days. If TgAb is positive, serum thyroglobulin is measured by an RIA method.

What is Thyroglobulin (Tg)?

Thyroglobulin (Tg) is synthesized exclusively by thyroid follicular cells as the precursor protein for thyroid hormone biosynthesis. 1,4,5 The serum Tg reflects the integrated sum of Tg released into the blood stream and is related to three factors: 1.

What is the prevalence of thyroglobulin antibody (TgAb) in the US?

Thyroglobulin antibody (TgAb) is detected in approximately 10% of the general population and in 20% of patients with DTC. 4,6-8 Several studies have suggested that the quantitative TgAb concentrations can serve as a surrogate tumor marker for DTC recurrence and for monitoring changes in tumor mass in certain patients. 9