What is hyper CVAD chemotherapy?

What is hyper CVAD chemotherapy?

An abbreviation for a chemotherapy combination used to treat some types of acute lymphoblastic leukemia (ALL) and non-Hodgkin lymphoma (NHL). Hyper-CVAD includes the drugs cyclophosphamide, vincristine sulfate, doxorubicin hydrochloride (Adriamycin), and dexamethasone.

What is pomp regimen?

POMP (6-Mercaptopurine + Vincristine + Methotrexate + Prednisone) is a Treatment Regimen for Acute Lymphoid Leukemia (ALL)

How long is induction therapy for ALL?

Induction therapy usually lasts for 29 days followed by a 1-week rest from chemotherapy. During induction, drugs will be given intravenously (IV) or through an intrathecal (IT) or orally (by mouth): If a drug is given intravenously, an IV is used to deliver medicine directly into your child’s vein.

How is hyper-CVAD given?

HyperCVAD Part A usually requires a 4 – 5 day stay in a hospital. Typically, cyclophosphamide, doxorubicin, vincristine, and dexamethasone are all given in the hospital on Days 1 – 4 of each cycle. Vincristine may be given in the clinic on Day 11 and dexamethasone is usually taken at home on Days 11 – 14.

What does Hyper-CVAD stand for?

The term ‘hyper’ refers to the hyperfractionated nature of the chemotherapy, which is given in smaller doses, more frequently, to minimize side effects. ‘CVAD’ is the acronym of the drugs used in course A: cyclophosphamide, vincristine, doxorubicin (also known by its trade name, Adriamycin), and dexamethasone.

How long is treatment for AML?

Chemotherapy is the primary treatment for acute myeloid leukemia (AML) in children. Multiple chemotherapy treatments are required for a chance at long-term cure. The length of chemotherapy treatment is usually >6 months. Some patients may receive a bone marrow transplant following initial chemotherapy.

What Calgb 10403?

CALGB 10403 was the largest prospective study to evaluate the feasibility of using a pediatric regimen in AYAs with acute lymphoblastic leukemia up to 40 years of age.

What happens after induction chemo?

Following successful induction therapy, patients with high-risk ALL are given one cycle of intensive consolidation chemotherapy. When the blood counts begin to return to normal after consolidation therapy, stem cells are collected from the blood using a technique called apheresis.

Is induction therapy the same as chemotherapy?

An induction therapy is the first treatment for a disease. Induction therapies are also called first-line therapies or primary therapies. Chemotherapy can be used at different points in your cancer treatment: Concurrent chemotherapy radiation therapy is when chemotherapy and radiation therapy are performed together.