What is the indication for ELIQUIS?
What is the indication for ELIQUIS?
Eliquis (apixaban) range of indications Treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE), and prevention of recurrent DVT and PE in adults. Prevention of venous thromboembolic events (VTE) in adult patients who have undergone elective hip or knee replacement surgery.
What are the contraindications for ELIQUIS?
Contraindications / Precautions
- General Information. Apixaban is contraindicated for use by patients with severe hypersensitivity to the drug.
- Bleeding.
- Abrupt discontinuation.
- Prosthetic heart valves.
- Surgery.
- Hepatic disease.
- Dialysis, geriatric, renal failure, renal impairment.
- Labor, obstetric delivery, pregnancy.
What is the action of ELIQUIS?
ELIQUIS inhibits free and clot-bound factor Xa, and prothrombinase activity. ELIQUIS has no direct effects on platelet aggregation, but indirectly inhibits platelet aggregation induced by thrombin. By inhibiting factor Xa, ELIQUIS prevents thrombin generation and thrombus development.
What are the indications for anticoagulants?
Anticoagulation is an important component of the management strategy for several common medical conditions. It is indicated for the prevention of recurrent thrombosis in patients with venous thromboembolism (VTE), which includes deep venous thrombosis and pulmonary embolism, and ischemic stroke.
What is ELIQUIS 5 mg used for?
Uses The FDA approved Eliquis to: reduce the risk of stroke and embolism in patients with nonvalvular atrial fibrillation; prevent blood clots in hip or knee replacement patients; treat deep-vein blood clots; and reduce the risk of blood clots recurring.
When is ELIQUIS prescribed?
ELIQUIS (apixaban) is indicated to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation. ELIQUIS is indicated for the prophylaxis of deep vein thrombosis (DVT), which may lead to pulmonary embolism (PE), in patients who have undergone hip or knee replacement surgery.
What is eliquis 5 mg used for?
Is 5mg of eliquis a lot?
The recommended dose of ELIQUIS for most patients is 5 mg taken orally twice daily. The recommended dose of ELIQUIS is 2.5 mg twice daily in patients with at least two of the following characteristics: age greater than or equal to 80 years.
Can eliquis affect creatinine levels?
After starting apixaban, serum creatinine significantly increased (from 3.2 to 8.5 mg/dL) within a few days, and the patient became oligoanuric. This was associated with new hematuria. All of these clinical symptoms have been seen in patients with WRN or dabigatran-associated AKI.
How often should aPTT be checked?
The aPTT is evaluated every 6 hours during the first day of heparin therapy and 6 hours after any dosage change. If the aPTT is therapeutic, it can be checked once daily while patients are on heparin.
How long should you take ELIQUIS?
If you have had a blood clot (DVT or pulmonary embolism), you’ll normally take apixaban for at least 3 months. Depending on what caused the blood clot, you might need to take it for longer. If you have atrial fibrillation, you might need to take apixaban long term or even for the rest of your life.
What is the recommended dose of Eliquis for most patients?
The recommended dose of ELIQUIS for most patients is 5 mg taken orally twice daily. 2.2 Dosage Adjustments The recommended dose of ELIQUIS is 2.5 mg twice daily in patients with any 2 of the following characteristics: age 80 years
How many tabs are in Eliquis DVT-PE treatment?
Images BRAND FORM. Eliquis DVT-PE Treatment 30-Day Starter 5 mg (74 tabs) tablet Eliquis oral – 5 mg tablet Eliquis oral – 2.5 mg tablet
What are the contraindications for eleliquis?
ELIQUIS is contraindicated in patients with the following conditions: Active pathological bleeding [see Warnings and Precautions (5.2) and Adverse Reactions (6.1)] Severe hypersensitivity reaction…
What is Eliquis used for after hip surgery?
Eliquis is also used after hip or knee replacement surgery to prevent a type of blood clot called deep vein thrombosis (DVT), which can lead to blood clots in the lungs (pulmonary embolism). Eliquis is also used to treat DVT or pulmonary embolism (PE), and to lower your risk of having a repeat DVT or PE.
