What is periarticular osteoporosis?

What is periarticular osteoporosis?

Abstract. Background: Periarticular osteoporosis is an early finding in the hands of patients with rheumatoid arthritis (RA), due to release of bone resorbing cytokines from the inflamed synovium. There has been disagreement as to whether periarticular bone loss occurs in psoriatic arthritis (PsA).

What is the diagnostic test for osteoporosis?

To diagnose osteoporosis and assess your risk of fracture and determine your need for treatment, your doctor will most likely order a bone density scan. This exam is used to measure bone mineral density (BMD). It is most commonly performed using dual-energy x-ray absorptiometry (DXA or DEXA) or bone densitometry.

What causes periarticular demineralization?

Generalized bone loss may result from immobility, the inflammatory process per se, and treatments such as steroids. On the other hand, periarticular demineralization occurs because of local release of inflammatory molecules and is the earliest feature of RA, preceding bone erosion.

What are periarticular erosions?

periarticular erosions, chondrocalcinosis, vascular calcifications and aseptic bone necrosis (fig. 1). Periarticular erosions were defined as localized resorption of cortical bone and underlying. spongious bone around the capsular insertion.

How is osteopenia diagnosis?

In order to diagnose osteopenia, your doctor will do a bone density test. Bone density measures bone mass and bone strength. One type of test is a dual-energy X-ray absorptiometry (DEXA or DXA). It measures bone density in your hips, spine, and wrist.

What is mild periarticular osteopenia?

Periarticular osteopenia is an indication of past inflammation around a certain joint. This can be seen in conditions such as rheumatoid arthritis and does not necessarily indicate a decreased BMD throughout the bony skeleton.

What is the best test for bone density?

Dual-energy x-ray absorptiometry — Experts agree that the most useful and reliable bone density test is a specialized kind of x-ray called dual-energy x-ray absorptiometry, or DXA. DXA provides precise measurements of bone density at important bone sites (such as the spine, hip, and forearm) with minimal radiation.

What is erosive RA?

RA causes chronic inflammation, which leads to gradual bone erosion. Classic RA symptoms include swollen joints, joint stiffness, and joint pain. Some people also have fatigue and loss of appetite. RA often affects the smaller joints like your hands, feet, and fingers, so bone erosion can occur in these joints.

Can X-ray radiogrammetry detect periarticular osteoporosis in rheumatoid arthritis?

Abstract. Digital X-ray radiogrammetry (DXR) is an effective and sensitive modality for monitoring periarticular osteoporosis, which is among the earliest features of rheumatoid arthritis, preceding bone erosions. DXR is a promising technique, which can provide quantitative data that allow early diagnosis.

Can periarticular osteoporosis be used as outcome measures in rheumatoid arthritis?

Because periarticular osteoporosis in RA is also the first disease-related morphological sign before erosions and joint space narrowing occur, it has been proposed that quantitative hand bone estimates that identify periarticular osteoporosis be used as outcome measures in RA [ 1, 4 ].

What is the role of X-ray in the workup of osteoporosis?

Digital X-ray radiogrammetry (DXR) is an effective and sensitive modality for monitoring periarticular osteoporosis, which is among the earliest features of rheumatoid arthritis, preceding bone erosions. DXR is a promising technique, which can provide quantitative data that allow early diagnosis.

How is metacarpal osteopenia diagnosed using X-ray scoring?

X-ray scoring methods are designed to allow semiquantitative measurement of radiographically visible disease-related alterations, in particular erosions and joint space narrowing caused by cartilage damage. However, metacarpal osteopenia predates periarticular erosions and joint destruction [ 2 – 4, 7 ].