How is oligodendroglioma diagnosed?
How is oligodendroglioma diagnosed?
Tests and procedures used to diagnose oligodendroglioma include:
- Neurological exam. During a neurological exam, your doctor will ask you about your signs and symptoms.
- Imaging tests. Imaging tests can help your doctor determine the location and size of your brain tumor.
- Removing a sample of tissue for testing (biopsy).
Can a CT scan detect glioblastoma?
Computed Tomography CT scan results offer a relatively high degree of confidence for the diagnosis of glioblastoma multiforme (GBM; malignant glioma).
How can you tell the difference between oligodendroglioma and astrocytoma?
Their names refer to the kind of cells in which they begin: Astrocytoma affects the glial cells called astrocytes. The most aggressive astrocytoma is a glioblastoma, which is also called a glioblastoma multiforme. Oligodendroglioma affects the glial cells called oligodendrocytes.
Can oligodendroglioma be benign?
Oligodendrogliomas can be malignant (cancer) or benign (not cancer). Some of these tumors grow quickly, but many are slower.
Can a CT miss a brain tumor?
In most cases, a CT scan is sufficient to rule out a large brain tumor. However, in cases where CT scan detects an abnormality or if your doctor thinks that you have enough signs and symptoms which need more detailed scanning, he/she might order an MRI.
Can grade 2 oligodendroglioma be cured?
Oligodendroglioma (grade II): In some cases, an oligodendroglioma can be cured. They are most likely to be diagnosed in adults, although they do occur in young children. Rarely this tumour can spread within the central nervous system, in the fluid that circulates around the brain and spinal cord.
What is the anatomy of oligodendroglioma?
Theoligodendroglioma anatomic situation and tumoral limits are better defined on MRI than on CT scanning. A large proportion of oligodendrogliomas is peripherally situated, and the tumor usually involves the whole thickness of the cortex. MRI is particularly reliable for appreciating cortical involvement.
What are the imaging features of 1p/19q codeleted oligodendroglioma?
The imaging features of the 1p/19q codeleted genotype that are considered typical of oligodendroglioma include indistinct tumor margin, heterogeneous signal intensity, and calcifications. [ 3, 15]
What are the treatment options for anaplastic oligodendroglioma?
Treatment. Treatment is mainly based on maximal surgical resection and focal radiotherapy. Chemotherapy can be adjuvant or neoadjuvant, above all in anaplastic oligodendroglioma, which are chemosensitive. Procarbazine, CCNU, and vincristine (PCV); temozolomide; and antiangiogenic therapy are currently in use.
What is the structure and function of oligodendrocytes?
Oligodendrocytes (cells that cover and protect nerve cells in the brain and spinal cord) (Figure 3) line up in small groups and wrap their cell processes around the thicker axons in the CNS (central nervous system= brain+spinal cord), producing fatty white substance that covers nerves, called myelin.
