How is crude drug adulteration detected?
How is crude drug adulteration detected?
Several analytical techniques are suggested to detect adulteration in HM, such as infrared (6–8), nuclear magnetic resonance spectroscopy (6, 7) and high-performance liquid chromatography coupled with mass spectrometry (HPLC–MS) or tandem mass spectrometry (HPLC–MS-MS) (1, 6, 9).
What is adulteration of crude drugs?
– The term adulteration is defined as substituting original crude drug partially or wholly with other similar looking substances. The substance, which is mixed, is free from or inferior in chemical and therapeutic property.
What is drug adulteration in pharmacognosy?
OR Adulteration is broadly defined as admixture or substitution of original or genuine article/ drug with inferior, defective or otherwise useless or harmful substances. ADULTRANT : The adulterant must be some material which in both cheap and available in fairly large amounts.
How can we prevent adulteration of crude drug?
Preventing adulteration
- Don’t announce random drug tests in advance.
- Secure the collection site to prevent tampering.
- No handbags, jackets, hats etc.
- Require donor to wash his/her hands before giving the sample.
- Turn off or tape handles (especially hot water) to accessible faucets.
- Put a coloring agent in the commode.
What are the methods of evaluation of crude drugs?
Evaluation Of Crude Drugs.
- Organoleptic evaluation.
- Microscopic evaluation.
- Chemical evaluation.
- Physical evaluation.
- Biological evaluation.
What is physical evaluation of crude drugs?
In crude plant evaluation, physical methods are often used to determine the solubility, specific gravity, optical rotation, viscosity, refractive index, melting point, water content, degree of fibre elasticity, and other physical characteristics of the herb material.
What is adulteration discuss various types of adulteration?
Types of adulterants
| Type | Substances Added |
|---|---|
| Intentional Adulterants | Sand, marble chips, stones, mud, other filth, talc, chalk powder, water, mineral oil and harmful colour. |
| Incidental adulterants | Pesticide residues, droppings of rodents, larvae in foods. |
What is adulteration and evaluation?
Evaluation Methods of Adulteration Evaluation means determination of identity, quality and purity of any drug. There are different evaluation methods available by which we can detect any type of adulteration in the original drug.
What is organoleptic evaluation of crude drugs?
Organoleptic evaluation means the study of drugs using organs of senses. It refers to the methods of analysis like colour, odour, taste, size, shape, and special features, such as: touch, texture, etc. Obviously, the initial sight of the plant or extract is so specific that it tends to identify itself.
What is crude drug example?
Examples: Acacia, Agar, Benzoin, Beeswax, Cinchona, Cinnamon, Digitalis, Datura, Jalap, Kino, Ephedra, Linseed, Fennel, Mustard, Ginger, Isapagol, Nutmeg, etc. according to the drugs part are arranged (Grouped) of the plant or animal represented into organised (Cellular) drugs and unorganised ( Acellular ) drugs.
What is crude drugs classification?
Classification of crude drugs • Crude drug i.e Simple drug • Crude drugs are plant, animal or their parts which after collection are subjected only to drying or making them into transverse/ longitudinal slices pieces or peeling them in some cases. They exist in natural form.
What is adulteration evaluation?
Evaluation Methods of Adulteration Evaluation means determination of identity, quality and purity of any drug. There are different evaluation methods available by which we can detect any type of adulteration in the original drug.
What is adulteration of drugs?
In a broad sense, any change in an article that lowers its standard, quality or composition, irrespective of causes, is regarded as adulteration. An drug is regarded as adulterated if it does not conform to the standard or quality of the genuine drug by whose name it is sold or supplied. Crude drugs are adulterated by a number of illegal acts.
What is meant by adulteration by vegetative matter?
Adulteration by Vegetative Matter Adulteration due to the presence of vegetative matter from the same plant due to the faulty collection or intentionally adding excessive vegetative matter from the same plant. A part of same plant which is devoid of therapeutic action are mixed with the same drug.
Are senna leaves adulterated?
Senna leaves containing an excess amount of Senna stems or pods would be an admixed drug and thus it would be regarded as adulterated.
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