What is the molecular formula of procaine?
What is the molecular formula of procaine?
C13H20N2O2
Procaine/Formula
Is procaine soluble in water?
3.1. Procaine is an ester of p-aminobenzoic acid. Its solubility in water is 5 mg/ml and its melting point is 61°C. Its hydrochloride is very soluble in water and has a melting point between 154°C and 158°C. Procainamide hydrochloride is also very soluble in water and has a melting point between 166°C and 170°C.
What is procaine made up of?
Procaine is a benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.
Can procaine form hydrogen bonds?
In the absence of water, the lowest-energy geometry of protonated procaine is characterized by a strong intra-molecular hydrogen bond.
Is procaine still available?
Procaine was the only available LA for more than 40 years; in 1947 the first amide-linked local anesthetic (ALA), lidocaine, was synthesized. Today procaine is still used and achieves long-term therapeutic effects in CIM.
What is the Iupac name of procaine?
Procaine hydrochloride
| PubChem CID | 5795 |
|---|---|
| Structure | Find Similar Structures |
| Chemical Safety | Laboratory Chemical Safety Summary (LCSS) Datasheet |
| Molecular Formula | C13H21ClN2O2 |
| Synonyms | PROCAINE HYDROCHLORIDE 51-05-8 Procaine Hcl 2-(diethylamino)ethyl 4-aminobenzoate hydrochloride Procaine (hydrochloride) More… |
How is procaine used?
Procaine is taken by mouth or given as a shot for arthritis, “hardening of the arteries” in the brain (cerebral atherosclerosis), dementia, depression, hair loss, high blood pressure, and sexual performance problems. As a prescription-only injection, procaine is used for local anesthesia.
Is procaine still used?
Today procaine is still used and achieves long-term therapeutic effects in CIM. Nevertheless many physicians believe that ELAs, such as procaine and chloroprocaine, are highly allergenic.
What is the half life of procaine?
After intramuscular injection of procaine penicillin (33,000 I.U./Kg) plasma levels reached a peak at about 270 ng/ml and then declined with a half-life of about 9 hours.
Can procaine be given IV?
Penicillin G benzathine and penicillin G procaine injection should never be given intravenously (into a vein), because this may cause serious or life-threatening side effects or death.
What is the work of procaine?
Procaine penicillin is an antibiotic that fights bacteria in your body. Procaine penicillin is used to treat many different types of infections caused by bacteria, including syphilis (a sexually transmitted disease). Do not use this medication for any other infection that has not been checked by your doctor.
What is the molecular formula of procaine hydrochloride?
Procaine hydrochloride PubChem CID 5795 Structure Find Similar Structures Chemical Safety Laboratory Chemical Safety Summary (LCSS Molecular Formula C13H21ClN2O2 Synonyms PROCAINE HYDROCHLORIDE 51-05-8 Procaine
What is the molecular weight of procaine penicillin G?
Procaine penicillin G PubChem CID 5903 Molecular Weight 570.7 Component Compounds CID 4914 (Procaine) CID 5904 (Penicillin Date s Modify 2021-07-10 Create 2005-08-08
What type of ester is procaine?
Procaine is a benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol. It has a role as a local anaesthetic, a central nervous system depressant and a peripheral nervous system drug.
What is the difference between procaine and procainamide?
In 1935, Mautz [4] demonstrated that direct application of procaine (a compound that differs from Procainamide by replacement of the amide linkage by the ester structure), to the myocardium, elevated the threshold of ventricular muscle to electrical stimulation.
