How rare is Kikuchi-Fujimoto disease?
How rare is Kikuchi-Fujimoto disease?
Kikuchi’s disease, first identified in Japan during 1972, is extremely rare with fewer than 50 cases reported in the medical literature. It appears to affect young adults particularly, but can occur at any age. Early reports suggest that Kikuchi’s disease affects women more often than men by a 4:1 ratio.
Is Kikuchi-Fujimoto disease curable?
Kikuchi disease generally goes away (resolves) on its own within one to four months, with or without intervention. However, treatments are available to relieve some of the associated signs and symptoms. For example, nonsteroidal anti-inflammatory drugs (NSAIDs) may be used to ease lymph node tenderness and fever.
How is Kikuchi diagnosed?
Kikuchi-Fujimoto disease is generally diagnosed on the basis of an excisional biopsy of affected lymph nodes. No specific diagnostic laboratory tests are available. The results of a wide range of laboratory studies are usually normal.
What autoimmune disease causes swollen lymph nodes?
Autoimmune diseases that can cause swollen lymph nodes
- Juvenile rheumatoid arthritis.
- Rheumatoid arthritis (chronic autoimmune disease characterized by joint inflammation)
- Systemic lupus erythematosus (disorder in which the body attacks its own healthy cells and tissues)
What is Kikuchi-Fujimoto disease?
Kikuchi-Fujimoto disease also known as histiocytic necrotizing lymphadenitis, is an extremely rare benign (non-cancerous) condition of the lymph nodes 1). Kikuchi-Fujimoto disease was first described in Japan in 1972, by Japanese Pathologists Kikuchi and Fujimoto, is benign and self-limiting disease that mainly affects young women of Asian origin.
What is the history of Kikuchi disease?
INTRODUCTION Kikuchi disease, also called Kikuchi-Fujimoto disease or Kikuchi histiocytic necrotizing lymphadenitis, was originally described in young women and is a rare, benign condition of unknown cause usually characterized by cervical lymphadenopathy and fever.
What are the signs and symptoms of Kikuchi disease?
Kikuchi disease is a benign disease of the lymph nodes. The main sign of Kikuchi disease is usually swollen lymph nodes in the neck, which tend to develop suddenly. Other signs and symptoms may include: [1] [2] This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person.
Is Kikuchi disease related to systemic lupus erythematous?
Kikuchi disease has been found to be associated with several autoimmune diseases, especially systemic lupus erythematous (SLE or lupus). Cases include those in which SLE began before Kikuchi disease, at the same time as Kikuchi disease, and in a few cases, several years after Kikuchi disease.
