What drugs interact with amikacin?

What drugs interact with amikacin?

Moderate Interactions

• AMINOGLYCOSIDES/SELECT CEPHALOSPORINS.
• AMINOGLYCOSIDES/PENICILLINS.
• AMINOGLYCOSIDES/LOOP DIURETICS.
• SELECTED NEPHROTOXIC AGENTS/CISPLATIN.
• SELECTED NEPHROTOXIC AGENTS/ADEFOVIR.
• SELECTED NEPHROTOXIC AGENTS/IMMUNE GLOBULIN IV (IGIV)
• SELECTED NEPHROTOXIC AGENTS/TENOFOVIR.

What are the side effects of Erythromycin Stearate?

Nausea, vomiting, diarrhea, stomach pain/cramping, and loss of appetite may occur. Taking this medication with food may lessen these symptoms. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Is amikacin safe in renal failure?

Conclusion: Amikacin usage in described, lowered doses with prolonged interval between them is safe in terms of ototoxicity and nephrotoxicity in patients with chronic kidney disease. Every two days dosage is less effective than every day dosage in patients with stage 4 CKD.

Is amikacin injection safe?

Amikacin injection is usually used for serious bacterial infections for which other medicines may not work. However, it may also cause some serious side effects, including damage to your hearing, sense of balance, and kidneys. These side effects may be more likely to occur in elderly patients and newborn infants.

What is erythromycin used for in humans?

Erythromycin is used to prevent and treat infections in many different parts of the body, including respiratory tract infections, skin infections, diphtheria, intestinal amebiasis, acute pelvic inflammatory disease, Legionnaire’s disease, pertussis, and syphilis.

How long does amikacin stay in your system?

In adults with normal renal function the plasma elimination half-life of amikacin is usually 2-3 hours. 94 – 98% of a single IM or IV dose of amikacin is excreted unchanged by glomerular filtration within 24 hours.

Is amikacin used for UTI?

Amikacin is a highly effective aminoglycoside, highly effective against extended spectrum beta lactamase (ESBL) bacteria. Older patients suffer from more urinary tract infection (UTIs), and have a higher frequency of infection with resistant bacteria, mainly among frail nursing home residents.

Does amikacin affect the kidneys?

Amikacin can harm your kidneys. This effect is increased when you also use certain other medicines, including: antivirals, chemotherapy, injected antibiotics, medicine for bowel disorders, medicine to prevent organ transplant rejection, injectable osteoporosis medication,…

What is an example of a pharmacokinetic interaction?

A pharmacokinetic interaction may occur if one drug affects another drug’s absorption, distribution, metabolism, or excretion. Examples can help to explain these complicated mechanisms: Absorption: Some drugs can alter the absorption of another drug into your bloodstream. For example, calcium can bind with some medications and block absorption.

What are the contraindications for the use of amikacin?

A history of hypersensitivity to amikacin is a contraindication for its use. A history of hypersensitivity or serious toxic reactions to aminoglycosides may contraindicate the use of any other aminoglycoside because of the known cross-sensitivities of patients to drugs in this class.

What happens if I skip a dose of amikacin?

Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Amikacin will not treat a viral infection such as the flu or a common cold. If you need surgery, tell the surgeon ahead of time that you are using amikacin.