Is pemphigus vulgaris a bullous disease?

Is pemphigus vulgaris a bullous disease?

Background: Autoimmune bullous diseases are rare conditions characterized by blistering of the skin and mucous membranes. The 2 commonest forms are pemphigus vulgaris and bullous pemphigoid.

What is the difference between mucous membrane pemphigoid and pemphigus vulgaris?

Conclusion: Oral MMP presents primarily as desquamative gingivitis, infrequently involving extragingival sites, and is highly amenable to topical therapy, while PV is a systemic mucocutaneous disease with extensive non-gingival oral lesions that almost always requires systemic therapy.

What is the difference between pemphigus vulgaris and Foliaceus?

Pemphigus foliaceus is confined to the skin, and there is little or no involvement of mucous membranes. This is in contrast to pemphigus vulgaris where there may be extensive mucous membrane involvement (mouth, eyelids etc.).

Is bullous pemphigoid a type of pemphigus?

Bullous pemphigoid usually involves pruritic bullae and/or urticarial plaques that occur most commonly in the groin, axillae, and flexural areas. Unlike pemphigus, involvement of the oropharyngeal mucosa occurs in only 1/3 of cases. It generally occurs as a more sudden widespread eruption, compared to pemphigus.

What is bullous pemphigoid caused by?

Bullous pemphigoid is most common in older adults. Bullous pemphigoid occurs when your immune system attacks a thin layer of tissue below your outer layer of skin. The reason for this abnormal immune response is unknown, although it sometimes can be triggered by taking certain medications.

Is bullous pemphigoid same as mucous membrane pemphigoid?

Although both bullous pemphigoid and MMP may affect skin and mucosa, the classical clinical findings in bullous pemphigoid are tense, fluid-filled bullae on skin, whereas the prevailing clinical feature in MMP is mucosal involvement.

Where are the bullae in pemphigus Foliaceus?

Pemphigus foliaceus blisters form in the superficial layers of the epidermis. Pemphigus vulgaris blisters can form at any epidermal level but typically form in the lower aspects of the epidermis. Bullous pemphigoid blisters form subepidermally (lamina lucida of the basement membrane zone).

Is pemphigus vulgaris an autoimmune disease?

Pemphigus is a rare group of autoimmune diseases. It causes blisters on the skin and mucous membranes throughout the body. It can affect the mouth, nose, throat, eyes, and genitals. Pemphigus vulgaris is the most common type of pemphigus.

Is bullous pemphigoid an autoimmune disease?

Bullous pemphigoid (BP) is a rare, autoimmune, chronic skin disorder characterized by blistering, urticarial lesions (hives) and itching. Less commonly these blisters can involve the mucous membranes including the eyes, oral mucosa, esophagus and genital mucosa.