What exactly does spermatogenesis involve?

What exactly does spermatogenesis involve?

Spermatogenesis consists of the mitotic division of spermatogonia, meiosis of spermatocytes, and postmeiotic differentiation of spermatids, processes tightly controlled by hormones and growth factors secreted by testicular somatic cells.

What is required for spermatogenesis?

Testosterone is required for processes that are critical for spermatogenesis including maintaining the BTB, supporting the completion of meiosis, the adhesion of elongated spermatids to Sertoli cells and the release of sperm.

What are the spermatogenesis steps?

There are three steps in spermatogenesis: 1) meiosis, during which the number of chromosomes in the cell is reduced to half or 23 chromosomes each; 2) meiosis II, during which each haploid cell forms spermatids; and 3) spermiogenesis, during which each spermatid develops into a sperm cell with a head and tail.

How is spermatogenesis maintained?

The development and maintenance of spermatogenesis is dependent on the pituitary gonadotropins; FSH, and LH. Both hormones are secreted and regulated as a part of the HPG axis in response to the hypothalamic gonadotropin-releasing hormone (GnRH).

How do Sertoli cells support spermiogenesis?

Sertoli cells facilitate the progression of germ cells to spermatozoa via direct contact and by controlling the environment milieu within the seminiferous tubules. The regulation of spermatogenesis by FSH and testosterone occurs by the action of these hormones on the Sertoli cells.

Does spermatogenesis involve mitosis?

Spermatogenesis is a complex process involving mitotic cell division, meiosis and the process of spermiogenesis.

Which induces the process of spermatogenesis?

Spermatogenesis begins when the hypothalamus releases a pulse of gonadotrophin-releasing hormone that induces the release of pituitary luteinizing hormone (LH) and follicle stimulating hormone. LH stimulates Leydig interstitial cells to synthesize and secrete testosterone.

What is spermatogenesis in biology?

Spermatogenesis Spermatogenesis is the process of formation of mature sperm cells through a series of mitotic and meiotic divisions along with metamorphic changes in the immature sperm cell. It is the male version of gametogenesis which results in the formation of mature male gametes.

What is the last stage of spermatogenesis?

Spermiogenesis is the last stage of spermatogenesis where the spermatids undergo changes in the shape and structure to form a mature sperm cell. The spermatids retain the structure of epithelioid cells for a short time but soon change into an elongated structure called spermatozoa. A spermatozoon consists of a head and a tail.

What happens to the shape of cells during spermatocytogenesis?

While the cells during the stage of spermatocytogenesis are typically rounded in appearance, they will dramatically change this configuration when they enter spermiogenesis, where they will have to be adapted for fertilization.

What are the immature cells of the sperm called?

The immature cells called spermatogonia are formed from these stem cells. The stem cells divide mitotically of which, the first half develop to form sperm cells, whereas the rest remain as stem cells to provide a continuous flow of stem cells in the tubules. These cells then migrate towards Sertoli cells.