What is the purpose of phosphoric acid in acetylation of ferrocene?
What is the purpose of phosphoric acid in acetylation of ferrocene?
Acetic anhydride and phosphoric acid react to form the acylium ion electrophile. The nucleophile ferrocene attacks the electrophile giving acetylferrocene.
How can you increase the yield of acetylferrocene?
In order to add an acetyl group to ferrocene all we need to do is react it with acetic anhydride (the source of the acetyl group) and some phosphoric acid. When these three components are mixed together the reaction happens quite smoothly and gives acetylferrocene in high yield.
Which is more polar Acetylferrocene or Diacetylferrocene?
1) Consider the compounds ferrocene, acetylferrocene, and diacetylferrocene. a. Which is the most polar and which is the least polar? Answer: Diacetylferrocene is most polar; ferrocene is least polar.
What is the formula of ferrocene?
C10H10Fe
Ferrocene/Formula
Which is more polar ferrocene or Acetylferrocene How do you know?
Answer: Diacetylferrocene is most polar; ferrocene is least polar.
What is the acetylation reaction of ferrocene?
An important thing to realize is that the acetylation reaction is a substitution reaction, one in which a hydrogen atom on the cyclopentadienyl ring is substituted for the acetyl group. Ferrocene is an organometallic compound made of iron, carbon, and hydrogen that’s considered the ‘prototypical’ metallocene.
Can ferrocene be acylated by acetic anhydride?
Thus, while the Friedel-Crafts acylation of benzene requires aluminum chloride as a catalyst, ferrocene can be acylated by acetic anhydride under milder conditions using phosphoric acid as the catalyst. In addition, the second ring may also be acetylated to give 1,1′-diacetylferrocene, Fe(C5H4COCH3)2.
What is Friedel Crafts acylation of ferrocene?
Experiment 14: The Friedel-Crafts Acylation of Ferrocene. A Friedel-Crafts acylation is an electrophilic aromatic substitution reaction that introduces an acyl group onto an aromatic ring. The electrophile is an acyl cation that is often coupled to a Lewis acid catalyst, such as aluminum chloride.
How do you add acetyl group to ferrocene?
In order to add an acetyl group to ferrocene all we need to do is react it with acetic anhydride (the source of the acetyl group) and some phosphoric acid. When these three components are mixed together the reaction happens quite smoothly and gives acetylferrocene in high yield.
