What is HSA miRNA?
What is HSA miRNA?
The “hsa” tells us it is a human miRNA. The “20″ tells us that was discovered early — it’s only the 20th family that was named. “20b” tells us that it is related to another miRNA that we can guess is probably called hsa-mir-20a.
What is HSA miR 27b?
Entrez Gene Summary for MIR27B Gene microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs.
What is PRI miR?
MicroRNAs (miRNAs) are small, regulatory RNAs that are expressed in animals and plants and affect the translation or stability of target mRNAs. The pri-miRNAs, which can be more than 1000 nt in length, contain an RNA hairpin in which one of the two strands includes the mature miRNA [1].
What is miR 125b?
MiR-125b acts as an oncogene in glioblastoma cells and inhibits cell apoptosis through p53 and p38MAPK-independent pathways. Br J Cancer. 2013;109(11):2853–2863.
How does a riboswitch control protein production?
In molecular biology, a riboswitch is a regulatory segment of a messenger RNA molecule that binds a small molecule, resulting in a change in production of the proteins encoded by the mRNA.
What is the direct target of mir125b?
Mechanistically, we confirmed that A20 was a direct target of miR-125b, and found that activation of nuclear factor κB (NF-κB) signaling pathway by A20 mediated miR-125b-promoting NPC cell proliferation and -inhibiting NPC cell apoptosis.
Are miRNA good or bad?
miRNAs can be classified with regard to their role in cancer as the Good, the Bad and the Ugly. The “Good”, those miRNAs that are innocent bystanders in the oncogenic transformation process, whose expression profile might even be used for cancer diagnosis or prognosis.
What is 5p and 3p miRNA?
In the precursor miRNA stem loop structure, the 5p strand is present in the forward (5′-3′) position and 3p strand (which will be almost complimentary to the 5p strand) is located in the reverse position.
