What is beta thalassemia Wiki?
What is beta thalassemia Wiki?
Beta thalassemias (β thalassemias) are a group of inherited blood disorders. They are forms of thalassemia caused by reduced or absent synthesis of the beta chains of hemoglobin that result in variable outcomes ranging from severe anemia to clinically asymptomatic individuals.
What causes B thalassemia?
Beta thalassemia is caused by mutations in the hemoglobin beta (HBB) gene. Individuals with beta thalassemia minor have a mutation in one HBB gene, while individuals with the intermediate and major forms have mutations in both HBB genes.
What is beta minus thalassemia?
Beta-0 thalassemia refers to the absence of production of beta globin. When patients are homozygous for a beta0 thalassemia gene, they cannot make any normal beta chains (hemoglobin A). Beta + thalassemia indicates a mutation that presents decreased but not absent production of beta globin.
Can thalassemia minor get married?
Thalassemia, related to the reduction in red blood cells, is rapidly increasing in India forcing doctors to make a fervent appeal for improved awareness and preventive measures at primary and social levels. No two Thalassemia minor patients should be allowed to marry.
Is beta thalassemia serious?
Beta thalassemia major (also called Cooley’s anemia). People with beta thalassemia major have severe symptoms and life-threatening anemia. They need regular blood transfusions and other medical treatment.
What is the life expectancy of someone with thalassemia?
Beta thalassemia intermedia also have a normal life span with proper treatment and management of beta thalassemia. The average life expectancy of a person with beta thalassemia major is about 17 years, most of the time by the age of 30 they die due to iron overload causing cardiac complications.
What foods are good for thalassemia?
Liver tonics that are sweet and oily are best for thalassemia minor, especially coconut. Favor cooling summer berries like blueberries and strawberries. Mild bitters like well cooked kale cooked with coconut oil help flush liver toxicity without draining the liver of strength (ojas).
What is the difference between thalassemia minor and major?
• Thalassemia major patient is dependent on regular blood transfusion throughout life where as thalassemia minor is a healthy person but with slightly lower hemoglobin level. • Thalassemia major is caused by mutation of both hemoglobin genes where as thalassemia minor is caused by mutation of one gene.
How do you diagnose thalassemia?
If your doctor is trying to diagnose thalassemia, they’ll likely take a blood sample. They’ll send this sample to a lab to be tested for anemia and abnormal hemoglobin. A lab technician will also look at the blood under a microscope to see if the red blood cells are oddly shaped. Abnormally shaped red blood cells are a sign of thalassemia.
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