Is arsenic trioxide chemotherapy?
Is arsenic trioxide chemotherapy?
Arsenic trioxide is a chemotherapy drug and is also called Trisenox or ATO. It is a treatment for a type of acute myeloid leukaemia called acute promyelocytic leukaemia (APL).
Is arsenic trioxide toxic?
Arsenic trioxide (an odorless, tasteless, white or transparent, nonflammable solid) is one of the most toxic and prevalent forms of arsenic. The water solubility of arsenic salts varies depending on the salt. Arsenic trioxide is readily absorbed if ingested or inhaled, but only slowly absorbed through the skin.
Is arsenic trioxide a carcinogen?
been shown to cause lung cancer in humans and animals. a carcinogen. ► Arsenic Trioxide may damage the developing fetus.
What does arsenic oxide do to the body?
Ingesting (swallowing) high levels of inorganic arsenic can result in death. Lower levels of arsenic can cause nausea and vomiting, decreased red and white blood cells, abnormal heart rhythm, and numbness and tingling in the hands and feet.
How do you take arsenic trioxide?
How Arsenic Trioxide Is Given: Arsenic trioxide is administered via an intravenous (IV) injection over the course of one or two hours. This may be extended up to four hours if the patient has a vasomotor reaction (lightheadedness, change in blood pressure).
Why was arsenic used as medicine?
During their time, Hippocrates used the arsenic sulfides realgar and orpiment to treat ulcers, and Dioscorides used orpiment as a depilatory. Since then, arsenic and its derivatives have been found to be useful in treating diseases such as cancer and syphilis.
What is arsenic trioxide made from?
When metallic arsenides or arsenic-containing sulfides are roasted in air, and when arsenic-containing coal is burned, arsenic trioxide is formed. The vapors condense in the flues and on the walls of the stacks as a powder commonly called “white arsenic.” Some arsenic trioxide finds its way into the air.
Where does arsenic trioxide come from?
Arsenic trioxide can be generated via routine processing of arsenic compounds including the oxidation (combustion) of arsenic and arsenic-containing minerals in air.
What cancers are associated with arsenic?
Which cancers are associated with exposure to arsenic? Prolonged ingestion of arsenic-containing drinking water is associated with an increased risk of bladder cancer and skin cancer, and medical exposure to arsenic has been clearly associated with skin cancer in epidemiological studies.
