What is the most important treatment modality for resolution of intra abdominal infections?

What is the most important treatment modality for resolution of intra abdominal infections?

Management of IAI requires resuscitation, source control, and antibacterial treatment. The most important of these factors is source control, which, “encompasses all measures undertaken to eliminate the source of infection and to control ongoing contamination”[19].

What are intra abdominal infections?

Intra-abdominal infection (IAI) is a broad term that encompasses a number of infectious processes, including peritonitis, diverticulitis, cholecystitis, cholangitis, and pancreatitis. A common cause of IAI is appendicitis.

What are the symptoms of pneumatosis intestinalis?

Patients with PI commonly present with gastrointestinal symptoms, including nausea, vomiting, and abdominal pain, but some present with no symptomatology. It is a relatively uncommon condition, with an incidence in the general population estimated to be 0.03%.

Which antibiotic is best for abdominal infection?

Patients with severe community-acquired intra-abdominal infection should be treated empirically with antimicrobial regimens that have broad-spectrum activity against gram-negative organisms, such as meropenem (Merrem), imipenem/cilastatin (Primaxin), doripenem (Doribax), or piperacillin/tazobactam (Zosyn) as single …

What bacteria causes intra-abdominal infections?

Nearly all intra-abdominal infections are caused by multiple microorganisms that constitute the intestinal flora (aerobes and facultative and obligate anaerobes, with Enterobacteriaceae, enterococci and Bacteroides fragilis isolated most frequently).

What is a Pneumoperitoneum?

The term pneumoperitoneum refers to the presence of air within the peritoneal cavity.

How do I know if I have an abdominal infection?

Clinical features of intra-abdominal infection include fever; tachycardia; tachypnea; hypotension; local, referred, generalized or absent abdominal pain; anorexia; nausea and vomiting; diarrhea; abdominal fullness; distension; obstipation; shock; acidosis; and extra-abdominal organ failure.

Is pneumatosis intestinalis fatal?

Pneumatosis intestinalis (PI) is defined as the presence of gas in the bowel wall [1–4]. This imaging finding is associated with numerous conditions, ranging from benign to life threatening [1–5].

CAN flagyl treat sepsis?

Metronidazole is the only available antimicrobial agent providing selective activity against anaerobic organisms. It is effective and safe and is usually the drug of choice for treating severe anaerobic sepsis.

What are the side effects of metronidazole?

Stopping the medication too early may result in a return of the infection. Tell your doctor if your condition lasts or gets worse. Save up to 80% on your prescription with WebMDRx. Dizziness, headache, stomach upset, nausea, vomiting, loss of appetite, diarrhea, constipation, or metallic taste in your mouth may occur.

How many milligrams of metronidazole should I take before surgery?

Dosage of Metronidazole: Adult and Pediatric Dosage Forms and Strengths Dosage Considerations – Should be Given as Follows: 15 mg/kg IV over 30-60 min; complete approximately 1 hour before surgery; may administer 7.5 mg/kg IV over 30-60 min at 6 and 12 hours after initial dose for maintenance; discontinue within 12 hours after surgery

What are the different brand names for metronidazole?

Metronidazole is available under the following different brand names: Flagyl, Flagyl ER, and Flagyl IV RTU. Dosage of Metronidazole: Adult and Pediatric Dosage Forms and Strengths

How do you take metronidazole for upset stomach?

How to use Metronidazole. Take this medication by mouth as directed by your doctor. To prevent stomach upset, take this medication with food or a full glass of water or milk. The dosage is based on your medical condition and response to treatment.