Can steroids cause panniculitis?

Can steroids cause panniculitis?

Post-steroid panniculitis is a rare complication of systemic corticosteroid therapy, which develops within days or weeks following rapid tapering or cessation of the drug. Till date, 20 cases have been described in medical literature. [1] Most of the reported cases have been in children.

What is panniculitis and what causes it?

Panniculitis an umbrella term that describes inflammation in the bottom layers of the skin. It can be caused by a variety of infections, diseases, or external stimuli.

What is the treatment for panniculitis?

Medicines used to treat panniculitis include: nonsteroidal anti-inflammatory drugs such as aspirin (Bufferin) or ibuprofen (Advil) to bring down inflammation and relieve pain. antibiotics, such as tetracycline, to treat an infection. hydroxychloroquine, an antimalarial drug, to bring down inflammation.

How common is Panniculitis?

Panniculitis is a relatively uncommon skin disorder. It causes large bumps to appear under the skin, usually on the lower legs. The bumps, also called nodules, are tender to touch and may look red or purple. Nodules are caused by an inflammation in the layer of fat under the skin.

What is lupus panniculitis?

Lupus erythematosus panniculitis (LEP) is a rare variant of cutaneous lupus erythematosus characterized by tender, often painful, erythematous subcutaneous indurated nodules or plaques on fatty body areas. 1,2. Profound lipoatrophy often occurs, potentially leading to severe disfigurement.

What bacteria causes panniculitis?

Common bacteria that cause panniculitis include:

• Streptococcus pyogenes.
• Staphylococcus aureus.
• Pseudomonas spp.
• Klebsiella spp.
• Nocardia spp.
• Brucella spp.

What is cold panniculitis?

Cold panniculitis (CP) is an acute, nodular, erythematous eruption usually limited to areas exposed to the cold. Cold panniculitis results from a cold injury to adipose tissue.

What does mesenteric panniculitis feel like?

Clinical symptoms of mesenteric panniculitis are highly variable. Some individuals have few or no noticeable symptoms; others may be greatly affected by a variety of complaints including abdominal pain, nausea/vomiting, bloating, early satiety, loss of appetite and diarrhea or constipation.

What causes mesenteric panniculitis to flare up?

The specific cause of mesenteric panniculitis isn’t known, but may be related to autoimmune disease, abdominal surgery, injury to your abdomen, bacterial infection, or vascular problems. It causes chronic inflammation that damages and destroys fatty tissue in the mesentery.

Panniculitis refers to a group of conditions that involve inflammation of subcutaneous fat. Despite having very diverse causes, most forms of panniculitis have the same clinical appearance. The diagnosis is established by a skin biopsy, as there are characteristic microscopic features depending on the cause.

Which medications are used in the treatment of panniculitis?

If secondary infection is present, antibiotic therapy may be needed as well. The goal is to find, treat, and/or remove any underlying cause or trigger of the panniculitis.

Is panniculitis common in dogs?

Panniculitis is a common problem in cats, but is less so in dogs. What causes panniculitis? In younger animals with a single lump, the cause is often blunt trauma. In cats, panniculitis is often caused by bite wounds from fighting. Other, much less common causes include:

Why is histopathology important in the diagnosis of panniculitis?

Histopathology can rule out other diseases, including cancer. Some forms of cancer resemble panniculitis. Because these cancers can be aggressive, early removal and examination of all lumps is important both for an accurate diagnosis and the development of a timely treatment plan.