What is Desquamative interstitial pneumonitis?

What is Desquamative interstitial pneumonitis?

Desquamative interstitial pneumonia (DIP) is characterised by the accumulation of numerous pigmented macrophages within most of the distal airspace of the lung and, sometimes, the presence of giant cells. Diagnosis of DIP is not easy and requires surgical lung biopsy. DIP is usually associated with tobacco smoke.

What causes Desquamative interstitial pneumonia?

Desquamative interstitial pneumonitis is an interstitial lung disease most commonly associated with smoking. It causes respiratory symptoms including indolent cough and dyspnea.

What is lymphocytic interstitial pneumonitis?

Lymphocytic interstitial pneumonia (LIP) is a syndrome of fever, cough, and dyspnea, with bibasilar pulmonary infiltrates consisting of dense interstitial accumulations of lymphocytes and plasma cells.

Does interstitial pneumonitis go away?

There is no cure for ILD. Once scarring happens in the lungs, it usually cannot be reversed. Treatment can help slow the disease down to preserve as much quality of life as possible. The prognosis for patients depends on how severe the condition is, and the cause of the ILD.

Is Desquamative interstitial pneumonitis fatal?

Treatment of Desquamative Interstitial Pneumonia Patients who do not improve may respond to corticosteroids or cytotoxic drugs. Prognosis is good, with about 70% survival at 10 years.

What is Desquamative?

Desquamative inflammatory vaginitis is a form of vaginitis occurring primarily in perimenopausal white women. The etiology is unknown. The syndrome includes vaginal inflammation, rash and purulent discharge along with dyspareunia.

How long can you live with interstitial lung disease?

The average survival for people with this type is currently 3 to 5 years . It can be longer with certain medications and depending on its course. People with other types of interstitial lung disease, like sarcoidosis, can live much longer.

What causes lymphocytic interstitial pneumonitis?

Causes. Possible causes of lymphocytic interstitial pneumonia include the Epstein-Barr virus, auto-immune, and HIV.

How is lymphocytic interstitial pneumonia treated?

Treatment of lymphocytic interstitial pneumonia is with corticosteroids, cytotoxic drugs, or both, but, as with many other causes of interstitial lung diseases, the efficacy of this approach is unknown.

What is the most striking finding seen in Desquamative interstitial pneumonia?

The most striking feature is the presence of numerous pigmented macrophages within distal airspaces, mistaken as desquamated pneumocytes when the disease was first described. Honeycombing is rare.

How do you treat interstitial pneumonia?

A lung transplant procedure may be the most effective treatment for usual interstitial pneumonia. Alveoli are empty sacs that swap waste carbon dioxide from the blood for fresh oxygen from the air. Pneumonia can quickly become life threatening.

What is treatment for interstitial pneumonia?

Treatment of acute interstitial pneumonia is supportive and usually requires mechanical ventilation, often using the same methods as used for ARDS (including low tidal volume ventilation). Corticosteroid therapy is generally used, but efficacy has not been established.

Is interstitial lung disease the same as COPD?

The interstitial lung disease (ILD) is not the same as COPD. In Interstitial lung disease, the interstitium of the lungs become thick and scarred, meaning that the air sacs become scarred too. In COPD, there is an obstruction of the airways and air sacs.

Does amiodarone cause interstitial lung disease?

Amiodarone lung is an interstitial lung disease seen in patients being administered amiodarone and can manifest in a number of histopathologic patterns. The reported prevalence of pulmonary toxicity in patients receiving amiodarone is ~10% (range 2-18%) 8.