What is hypertrophic lupus?
What is hypertrophic lupus?
Background: Hypertrophic lupus erythematosus (HLE) is a distinct and rare subset of lupus erythematosus (LE). It is characterized by verrucous lesions, chronic in its course, and resistant to treatment. The purpose of this study was to identify clinical and histological characteristics of HLE.
What is the meaning of lupus erythematosus?
Systemic lupus erythematosus (SLE), is the most common type of lupus. SLE is an autoimmune disease in which the immune system attacks its own tissues, causing widespread inflammation and tissue damage in the affected organs. It can affect the joints, skin, brain, lungs, kidneys, and blood vessels.
What is the scientific definition of lupus?
Lupus is a long-term autoimmune disease in which the body’s immune system becomes hyperactive and attacks normal, healthy tissue. Symptoms include inflammation, swelling, and damage to the joints, skin, kidneys, blood, heart, and lungs.
What are hypertrophic lesions?
Hypertrophic or verrucous DLE (hypertrophic LE) is a unique subset, in which unusual lesions occur. The thick, adherent scale is replaced by massive hyperkeratosis, and the lesions look like warts or squamous cell carcinomas. It was also described as verrucous lupus erythematosus or keratotic lupus erythematosus.
What is Hypertrophic Lichen Planus?
Hypertrophic lichen planus (HLP) is the second most common cutaneous variant of lichen planus. It is characterized as extremely pruritic, and thick hyperkeratotic plaques are seen primarily on the shins or dorsal aspect of the foot and may be covered by a fine adherent scale.
What is the basic pathophysiology of systemic lupus erythematosus?
Systemic lupus erythematosus (SLE, lupus) is characterized by a global loss of self-tolerance with activation of autoreactive T and B cells leading to production of pathogenic autoantibodies and tissue injury. Innate immune mechanisms are necessary for the aberrant adaptive immune responses in SLE.
What is Hak dermatology?
Hypertrophic actinic keratosis, a variant of actinic keratosis, is primarily caused by chronic sun and ultraviolet exposure.
