What is HBsAg E test?
What is HBsAg E test?
Detection of the viral antigens HBsAg (surface antigen of HBV) and HBeAg (the hepatitis “e” antigen) and their corresponding antibodies is the cornerstone of diagnostic management of HBV infection. Thus, the presence of HBsAg in serum for 6 months or longer is defined as a chronic infection.
What is e antigen negative hepatitis B?
Hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (CHB) occurs at the late phase in hepatitis B virus (HBV) infection’s natural history. The disease is characterized by progressive liver damage due to variants with mutations in the precore/core promoter region that reduce or abolish HBeAg expression.
What does HBeAb positive mean?
Those with a positive HBeAg have active replication in their liver cells, more of the virus circulating in their blood, and as a result, they are more infectious, with a higher likelihood of transmitting HBV to others. Most often, when a person is HBeAg positive, they tend to be HBeAb negative and vice-versa.
What does E in HBeAg stand for?
HBeAg stands for hepatitis B e-antigen. This antigen is a protein from the hepatitis B virus that circulates in infected blood when the virus is actively replicating.
What is E antibody?
Introduction. Antibodies with anti-E specificity are detected in 14–20% of pregnant women and it is one of the most common non-D Rhesus (Rh) antibody in the pathogenesis of neonatal hemolytic disease [1, 2]. However, anti-E is rarely associated with severe hemolytic anemia in the fetus [3, 4].
What is HBV-DNA?
HBV-DNA or hepatitis B virus DNA is a measure of the viral load of the hepatitis B virus in the blood. The result is expressed in international units per millilitre (IU/mL), with each unit representing approximately 6 viral particles per millilitre of blood.
Is HBsAg the same as HBeAg?
Hepatitis B e antigen (HBeAg) is a small polypeptide that exists in a free form in the serum of individuals during the early phase of hepatitis B infection, soon after hepatitis B surface antigen (HBsAg) becomes detectable. Serum levels of both HBeAg and HBsAg rise rapidly during the period of viral replication.
