Can pregnancy cause prolonged QT interval?
Can pregnancy cause prolonged QT interval?
Introduction: Prolongation of QT interval might result in dangerous cardiac arrhythmias, including Torsades de Pointes (TdP), consequently leading to syncope or death. A limited number of studies carried out in this respect to date have shown that QT interval might increase during pregnancy.
Which of the following drugs is contraindicated in patients with long QT syndrome?
Table 1
| Drugs to be avoided in patients with c-long QT syndrome | |
|---|---|
| Antibiotic | Moxifloxacin, Clarithromycin, Ciprofloxacin, Gemifloxacin, Ofloxacin Telithromycin, Levofloxacin, Roxithromycin, Trimethoprim-Sulfa, Gatifloxacin, Sparfloxacin, Azithromycin Erythromycin |
What antibiotics prolong QT interval?
Antimicrobials that are associated with QT prolongation include the macrolides/ketolides, certain fluoroquinolones and antimalarials, pentamidine, and the azole antifungals.
Does Atarax prolong QT?
The review concluded that hydroxyzine is associated with a small risk of QT interval prolongation and Torsade de Pointes. Such events are most likely to occur in patients who already have risk factors for QT prolongation, such as: concomitant use of medicines that prolong the QT interval.
Why is prolonged QT bad?
If the QT interval is prolonged, patients can be at risk for ventricular rhythm disturbances. That means, basically an electrical disorder of the lower chambers of the heart.
Does Rocephin prolong QT interval?
In the adverse event reports, the authors found that the combination of ceftriaxone (Rocephin), a cephalosporin antibiotic, and lansoprazole (Prevacid), a proton-pump inhibitor, prolongs the QT interval.
Does Benadryl prolong QTc?
A less known, but rare side effect of diphenhydramine is prolongation of QT interval. The histamine H1 receptor antagonist diphenhydramine inhibits the fast sodium channels and at higher concentrations inhibits the repolarizing potassium channels which leads to prolongation of the action potential and the QT interval.
