What is provocholine used for?
What is provocholine used for?
Provocholine (methacholine chloride) is a cholinergic drug that causes wheezing and shortness of breath and is used as a test to determine whether you may have asthma. Provocholine is only administered in a clinical setting and is used for testing and not to treat any conditions.
What drugs interact with theophylline?
TABLE II. Clinically significant drug interactions with theophylline.*
| Drug | Type of Interaction |
|---|---|
| Carbamazepine | Similar to aminoglutethimide. |
| Cimetidine | Decreases theophylline clearance by inhibiting cytochrome P450 1A2. |
| Ciprofloxacin | Similar to cimetidine. |
| Clarithromycin | Similar to erythromycin. |
What drug classification is theophylline?
This medication belongs to a class of drugs known as xanthines. It works by relaxing the muscles around the airways so that they open up and you can breathe more easily.
What is another name for theophylline?
If sudden shortness of breath occurs, use your quick-relief inhaler as prescribed. Theophylline is available under the following different brand names: Theo 24, Theochron, Elixophyllin, aminophylline, and Uniphyl.
How does a methacholine challenge work?
This test can show whether you have asthma by using a drug to simulate an asthma attack. You breathe in (inhale) a dose of methacholine to narrow your airways. Then, you take a breathing test (spirometry). You may repeat these steps depending on the test result.
Is theophylline still used for asthma?
Theophylline is still one of the most widely prescribed drugs for the treatment of asthma and chronic obstructive pulmonary disease (COPD) worldwide, because it is inexpensive and widely available.
Is theophylline good for asthma?
Theophylline is used to prevent and treat wheezing, shortness of breath, and chest tightness caused by asthma, chronic bronchitis, emphysema, and other lung diseases. It relaxes and opens air passages in the lungs, making it easier to breathe.
How do you add sodium chloride to Provocholine?
Add 6.25 mL of 0.9% Sodium Chloride Injection (0.9% saline) or 0.9% Sodium Chloride Injection with 0.4% phenol (0.9% saline with 0.4% phenol) to the supplied vials containing 100 mg of Provocholine powder Dilute the reconstituted Provocholine solution:
What are the side effects of Provocholine?
Provocholine is to be administered only by inhalation. When administered orally or by injection, methacholine chloride is reported to be associated with nausea and vomiting, substernal pain or pressure, hypotension,fainting and transient complete heart block.
How to obtain post-diluent FEV 1 values using Provocholine?
Provocholine dose (s) to obtain post-diluent FEV 1 values. 1. Using a 3 mL syringe and needle, draw up 2 to 3 mL of the diluent (0.9% saline or 0.9% saline with 0.4% phenol) and dispense into the nebulizer using a sterile bacterial-retentive filter (porosity 0.22 μm). 2.
What is Provocholine and the methacholine challenge test?
Provocholine is the only FDA approved methacholine chloride for the diagnosis of bronchial hyperresponsiveness. A negative methacholine challenge test can essentially rule out asthma. Here are the answers to the common questions about Provocholine and the methacholine challenge test.
