Why is alkaline phosphatase test ordered?

Why is alkaline phosphatase test ordered?

The alkaline phosphatase test (ALP) is used to help detect liver disease or bone disorders. It is often ordered along with other tests, such as a gamma-glutamyl transferase (GGT) test and/or as part of a liver panel. In conditions affecting the liver, damaged liver cells release increased amounts of ALP into the blood.

Why would a doctor order a hepatic function panel?

A liver (hepatic) function panel is a blood test to check how well the liver is working. This test measures the blood levels of total protein, albumin, bilirubin, and liver enzymes. High or low levels may mean that liver damage or disease is present.

Should I be concerned if my alkaline phosphatase is high?

High alkaline phosphatase levels may mean there is damage to your liver or that you have a type of bone disorder. Liver damage creates a different type of ALP than bone disorders do.

Is elevated alkaline phosphatase serious?

It’s important to note that elevated levels of ALP can range in severity. While a very high ALP level often means you have liver damage or a bone disorder, mildly elevated levels can be caused by many different factors — not necessarily a medical condition that needs treatment.

What is Alt in hepatic function panel?

Alanine aminotransferase (ALT). This enzyme,found in the liver,plays a role in metabolism,the process that converts food into energy.

  • Alkaline phosphatase (ALP). This enzyme is found in the liver,bones,intestines,kidneys,and other organs.
  • Aspartate aminotransferase (AST).
  • Total bilirubin and direct bilirubin.
  • Albumin and total protein.
  • What are the reasons for an elevated alkaline phosphatase?

    Liver disease. Alkaline phosphatase levels can change and increase as a consequence of different liver diseases.

  • Bone disease. One of the bone diseases that is known for elevating alkaline phosphatase if Paget’s disease.
  • Tumors.
  • Pregnancy.
  • Specific medications.
  • What are dangerous levels of alkaline phosphatase?

    In the normal adult population, the range of alkaline phosphatase is between 50 to 75 mg/dl. The assay must be performed only when the patient has fasted since ingestion of food will cause the level of the enzyme to rise in the bloodstream which can lead to erroneous clinical data.

    What causes increased alkaline phosphatase?

    A rise in the alkaline phosphatase occurs with all forms of cholestasis, particularly with obstructive jaundice. It is also elevated in diseases of the skeletal system, such as Paget disease, hyperparathyroidism, rickets and osteomalacia, as well as with fractures and malignant tumors.

    author

    Back to Top