Why Standardization is important for herbal drugs?
Why Standardization is important for herbal drugs?
Standardization guarantees the content of one or more active constituents and marker compounds. The plant environment and genetic factors could significantly affect the biochemical components of the plant extract, in which plants are still the most abundant and cost-effective resource for drug innovation.
WHO guidelines for standardization of herbal drugs include?
WHO Guidelines for Quality Standardized Herbal Formulations
- a.
- The bioactive extract should be standardized on the basis of active principles or major compounds along with the chromatographic fingerprints (TLC, HPTLC, HPLC and GC).
- Limits for Microbial Contamination.
What is standardization in pharmacognosy?
STANDARDISATION • Standardization of drug means “confirmation of its identity and determination of its quality and purity and detection of nature of adulterant by various parameters like morphological, microscopical, physical, chemical and biological observations.”
Which of the following method is used to standardized herbal products?
Thin-layer chromatography is commonly used for identification purposes but for herbal ingredients containing volatile oils, a gas–liquid chromatographic test may be used.
What is standardization of herbal drug?
Standardization of herbal drugs means confirmation of its identity, Quality and purity. The present overview covers the standardization parameters with their standards value of the some herbal drugs.
How do you preserve herbal medicine?
Using a bit of oil (olive oil works best), place your herbs inside an airtight jar or bottle alongside the oil. This method is an attractive and decorative option and will spruce up any kitchen space. Be sure to store in a cool or refrigerated place, especially during warmer months. Use within 6 months.
Which method is used for making of herbal preparations?
The herbal preparations thus obtained include extracts, decoctions, tinctures, essential oils and others. The processes involved include extraction, distillation, fractionation, concentration, fermentation, or other chemical or biological methods.
What is herbal standardization?
Standardization of herbal drugs means confirmation of its identity, Quality and purity. Standardization of drug means confirmation of its identity, quality and purity throughout all phases of its cycle i.e. shelf-life, storage, distribution and use by various parameters.
What are the factors that affect the stability of herbal drugs?
Phytoformulations often suffer degradation during storage by oxidation, hydrolysis, crystallization, emulsion breakdown, enzymatic deterioration and chemical reactions with the additives and excipients. Temperature and moisture are the two major factors that affect quality and stability of a herbal product.
What is standardization of plant?
Standardization of herbal medicinal plant is the process of prescribing a set of standards or inherent characteristics, constant parameters, definitive qualitative and quantitative values that carry an assurance of quality, efficacy, safety, and reproducibility.
Why standardization of herbal drugs is important?
Therefore evaluation of the parameters based upon chemical, physical, microbiological, therapeutic and toxicological studies can serve as an important tool in stability studies. Standardization of herbal drugs means confirmation of its identity, Quality and purity.
What are the main limitations of herbal medicines?
As the are prepared from herbs. The herbal medicines however, suffer from lack of standardization parameters. The main limitation is the lack of standardization of raw materials, of processing quality control. It is necessary to introduce measures on the regulation of herbal medicines to suitable standards & GMP.
What is whowho standardization of drugs?
WHO has set up guidelines for standardization of these drugs, which are used as a standard by the majority of countries. The standardization includes the exter- nal (macroscopy/microscopy) as well as internal examination/ash values, extractive values and many other parameters to identify, authentify and study its chemical composition.
What is a medicinal plant?
Keywords: Standardization, herbal drug, botanical, pharmacological, toxicological, parameters INTRODUCTION Medicinal plants are in use for the crude drugs by means of various parameters purpose of treatment of different ailments like morphological, microscopical, physical, since centuries.
