Where is the medullary sinus located?
Where is the medullary sinus located?
The medullary sinuses are the terminal continuations of the peripherally located cortical sinuses. They eventually culminate at the hilum of the lymph node to form efferent lymphatic vessels. Lymph vessels are lined by a single layer of squamous endothelium.
What is the difference between the cortex and medulla of the lymph node?
The body of the lymph node is divided into an outer cortex and an inner medulla. The cortex contains a high concentration of lymphocytes while the inner medulla is less cellular. Between the cortex and medulla lies an ill-defined region called the paracortex which is rich in T-cells.
What are lymphatic sinuses?
Endothelia-lined channels through which lymph flows inside lymph nodes. The walls of lymph sinuses are coated with T and B lymphocytes as well as phagocytic cells, all of which filter the passing lymph. Lymphocytes and macrophages move in and out of the lymph through the sinus walls.
What do medullary cords do?
The medullary cord is a dense structure in the lymph node, and it is composed of lymphatic tissue. These cords are found within the lymph node’s medulla, which is located in the center of the node. They function by producing antibodies that flow out of the lymph node via the lymph fluid.
What are medullary sinuses?
The medullary sinuses (or sinusoids) are vessel-like spaces that separate the medullary cords. The medullary sinuses receive lymph from the trabecular sinuses and cortical sinuses and contain reticular cells and histocytes. The medullary sinus drains the lymph into the efferent lymphatic vessels.
What does lymph node do?
A small bean-shaped structure that is part of the body’s immune system. Lymph nodes filter substances that travel through the lymphatic fluid, and they contain lymphocytes (white blood cells) that help the body fight infection and disease.
What are medullary sinuses made of?
Medullary sinuses contain histiocytes (immobile macrophages) and reticular cells. A lymph node contains lymphoid tissue, i.e., a meshwork or fibers called reticulum with white blood cells enmeshed in it. The regions where there are few cells within the meshwork are known as lymph sinus.
