How do you administer surfactant?
How do you administer surfactant?
Surfactant has been administered either by disconnecting the infant from the ventilator and applying bagging, or by continuing ventilation during the procedure.
How is lung surfactant administered?
Methods to deliver surfactant The surfactant is administered via a thin catheter into the trachea in small aliquots, while the baby is spontaneously breathing on CPAP support. In infants 29-32 weeks gestation, LISA may reduce the occurrence of pneumothorax and need for mechanical ventilation.
How are babies given surfactant?
Your baby may also be given a dose of artificial surfactant, usually through a breathing tube. Evidence suggests early treatment within 2 hours of delivery is more beneficial than if treatment is delayed. They’ll also be given fluids and nutrition through a tube connected to a vein.
When do we administer surfactant?
Ideally the dose should be given within 1 hr of birth but definitely before 2 hours of age. A repeat dose should be given within 4 – 12 hours if the patient is still intubated and requiring more than 30 to 40% oxygen.
How many times can you administer surfactant?
Infants with RDS who have persistent or recurrent oxygen and ventilatory requirements within the first 72 h of life should have repeated doses of surfactant. Administering more than three doses has not been shown to have a benefit (grade A).
How often can you give curosurf?
The initial recommended dose of CUROSURF is 2.5 mL/kg birth weight. Up to 2 repeat doses of 1.25 mL/kg birth weight each may be administered at approximately 12‑hour intervals. A total of 4 doses of Survanta (4 mL/kg birth weight) can be administered no more frequently than every 6 hours in the first 48 hours of life.
When do you administer curosurf?
How does surfactant affect airflow?
What effect does the addition of surfactant have on the airflow? AIrflow increases because resistance is reduced. Why does surfactant affect airflow? It decreases surface tension in the alveoli making it easier for the alveoli to increase surface area for gas exchange.
How does surfactant prevent alveolar collapse?
Surfactant is released from the lung cells and spreads across the tissue that surrounds alveoli. This substance lowers surface tension, which keeps the alveoli from collapsing after exhalation and makes breathing easy.
How do steroids stimulate surfactant?
The steroids stimulate (via the fibroblast-pneumonocyte factor) production of surfactant phospholipids by alveolar type II cells, enhance the expression of surfactant-associated proteins, reduce microvascular permeability, and accelerate overall structural maturation of the lungs.
How do you administer Curosurf suspension?
Insert the catheter into the endotracheal tube and instill the first aliquot of CUROSURF suspension. After the first aliquot is instilled, remove the catheter from the endotracheal tube and manually ventilate with supplemental oxygen until clinically stable.
What is the recommended dose of Curosurf?
The recommended initial dose of CUROSURF (poractant alfa) Intratracheal Suspension is 2.5 mL/kg birth weight. This dose may be determined from the CUROSURF dosing chart on the back of this booklet. Repeat Doses Up to 2 repeat doses of 1.25 mL/kg birth weight each may be administered.
What is Curosurf ® intratracheal suspension?
CUROSURF ® (poractant alfa) Intratracheal Suspension is indicated for the rescue treatment of Respiratory Distress Syndrome (RDS) in premature infants. CUROSURF reduces mortality and pneumothoraces associated with RDS. 2.1 Important Administration Instructions – For intratracheal administration only.
What are the side effects of currosurf?
CUROSURF should only be administered by those trained and experienced in the care, resuscitation, and stabilization of preterm infants. Transient adverse reactions associated with administration of CUROSURF include bradycardia, hypotension, endotracheal tube blockage, and oxygen desaturation.
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