What is APE software?

What is APE software?

ApE is a proprietary sequence editor using a modified GenBank format to save sequences. The software can be used for assembly of sequencing traces, virtual digests, sequence annotation, and schematic sequence representation. It was created and is maintained by Wayne Davis from the University of Utah.

What is a plasmid editor?

Description: Software tool for plasmid and sequence editing, annotating and drawing plasmid sequences. Used to view circular or linear maps of DNA sequences. Users can perform virtual digests whereby they select predefined DNA ladder, or specify their own, and visualize theoretical DNA fragments.

How do you highlight sequences in ape?

Open a sequence in APE and go to Enzymes. Here, various tools that can help in digests are available, such as Enzyme List, which shows a list of REs and the number of sites in the sequence for each one. By clicking select, the sites for the selected RE will be highlighted.

What is ape gene?

The APE gene contains four small introns (ranging 130 to 566 bp) and five exons, the first of which is untranslated. The location of APE in the human genome was mapped to chromosome 14, bands q11. 2-12, by fluorescence in situ hybridization of metaphase cells with DNA from the genomic clones and subclones.

What’s the difference between monkeys and apes?

The quickest way to tell the difference between a monkey and an ape is by the presence or absence of a tail. Almost all monkeys have tails; apes do not. Apes are generally more intelligent than monkeys, and most species of apes exhibit some use of tools.

Are plasmids double or single stranded?

A plasmid is a small, circular, double-stranded DNA molecule that is distinct from a cell’s chromosomal DNA. Plasmids naturally exist in bacterial cells, and they also occur in some eukaryotes. Often, the genes carried in plasmids provide bacteria with genetic advantages, such as antibiotic resistance.

How do you design primers for plasmid sequencing?

Here are a few things to keep in mind when designing your own primers.

  1. Primer length should be in the range of 18 to 22 bases.
  2. The primer should have GC content of 50% to 55%.
  3. Primers should have a GC-lock on the 3′ end.
  4. The melting temperature of any good primer should be in the range of 50OC to 55OC.

What makes chimps different from humans?

Scientists have long known that chimpanzees are closely related to humans and recent genetic sequencing has revealed that humans share 99 percent of their DNA with chimps. But when it comes down to developing facial features, the many difference lie with how that 99-percent-similar DNA is regulated and expressed.

What is ape plasmid editor?

ApE – A Plasmid Editor (software review) ApE is a proprietary sequence editor using a modified GenBank format to save sequences. The software can be used for assembly of sequencing traces, virtual digests, sequence annotation, and schematic sequence representation.

Is Ape a good program for Molecular Biology?

The website for ApE is nothing flashy or fancy (and for that matter, neither is the program itself), but it is fully functional and does the job well. This is a definite recommendation for any molecular biologist.

How do I download ape on my own computer?

Download the free ApE software if you want it on your own computer. All college-owned computers already have ApE installed so you can use those computers if you prefer. This tool is used by researchers all over the world. Access your sequence files. Click once on a file with the .seq suffix.

What are the alternatives to ape?

Alternatives to ApE – A plasmid Editor for all platforms with any license Benchling Online lab notebook software, including DNA design tools. SnapGene Viewer SnapGene Viewer is revolutionary software that allows molecular biologists to create, browse, and share richly annotated DNA sequence files up to 1 Gb in length.

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