What does dimerization mean in biology?
What does dimerization mean in biology?
What is dimerization? It is a process where two molecules of similar chemical composition come together to form a single polymer known as a dimer.
What does it mean when something Dimerizes?
A dimerization is an addition reaction in which two molecules of the same compound react with each other to give the adduct.
Is dimerization extracellular or intracellular?
Dimerization utilizing the extracellular domains, especially via covalent disulfide bond formation between cysteine residues has been shown to mediate dimerization of family C GPCRs such as the metabotropic glutamate receptors (Ray & Hauschild, 2000).
What is dimerization in DNA?
Pyrimidine dimers are molecular lesions formed from thymine or cytosine bases in DNA via photochemical reactions. The dimerization reaction can also occur among pyrimidine bases in dsRNA (double-stranded RNA)—uracil or cytosine. Two common UV products are cyclobutane pyrimidine dimers (CPDs) and 6–4 photoproducts.
What is a dimer in biology DNA?
Pyrimidine dimers are molecular lesions formed from thymine or cytosine bases in DNA via photochemical reactions. The dimerization reaction can also occur among pyrimidine bases in dsRNA (double-stranded RNA)—uracil or cytosine.
How are homodimers formed?
A protein homodimer is formed by two identical proteins. A protein heterodimer is formed by two different proteins. Most protein dimers in biochemistry are not connected by covalent bonds. An example of a non-covalent heterodimer is the enzyme reverse transcriptase, which is composed of two different amino acid chains.
What is dimeric form?
Definition of ‘dimeric’ 1. (of a molecule) composed of two identical simpler molecules ( monomers) The structure reveals a dimeric arrangement. 2. (of a compound) composed of molecules which are themselves composed of two identical simpler molecules (monomers)
What is the meaning of dimdimerize?
dimerize [ dahy-m uh-rahyz ] verb (used with or without object), di·mer·ized, di·mer·iz·ing.Chemistry. to form (a dimer), as in polymerization.
What is the verb for dimer?
verb (used with or without object), di·mer·ized, di·mer·iz·ing. Chemistry. to form (a dimer), as in polymerization.
What does dimerization of a receptor mean?
Dimerization Dimerization leads to transphosphorylation of the tyrosine kinase domains of the receptor with signaling via downstream intracellular pathways leading to cell activation and proliferation. From: Her2-Positive Breast Cancer, 2019
What is the purpose of the dimerization detection method?
This method detects small perturbations of the membrane ultra-structure or of a protein’s tendency to dimerize.
