What is Pluronic f 68?
What is Pluronic f 68?
Gibco® Pluronic® F-68 is a non-ionic surfactant used to control shear forces in suspension cultures. Pluronic® F-68 can also be used to reduce foaming in stirred cultures and reduce cell attachment to glass. Pluronic® F-68 is provided at a concentration of 10% and effective at a working concentration of 0.1%.
What is Pluronic acid?
Let us mention that Pluronic is a poloxamer, i.e., an amphiphilic copolymer composed of a central hydrophobic chain of polyoxypropylene (poly-propylene oxide) flanked by two hydrophilic chains of polyoxyethylene (polyethylene oxide).
What is Pluronic 17R4?
Pluronic® 17R4 is a difunctional block copolymer surfactant with terminal secondary hydroxyl groups. A nonionic surfactant that is 100% active and relatively non-toxic. Typical physical properties. Form. Liquid.
Who makes Pluronic?
2) with Pluronics® L61 and F127 micelles (SP1049C, currently developed by Supratek Pharma Inc.).
How do you make Pluronic?
Dissolve 1 g of Pluronic® F-127 in 10 mL distilled water to make a 10% (w/v) stock solution, or 2 g of Pluronic® F-127 in 10 mL of anhydrous dimethyl sulfoxide (DMSO) to make a 20% (w/v) stock solution. These may require heating from 40 to 50 °C for about 30 minutes. Store solution at room temperature.
What are the properties of surfactant?
Surfactants, or surface-active agents, are amphiphilic molecules. Their heads are polar, or hydrophilic, and their tails hydrophobic. They are soluble in both organic solvent and water. The surfactant reduces the surface tension of water by adsorbing at the liquid–gas interface.
What is a surfactant and what are its properties?
surfactant, also called surface-active agent, substance such as a detergent that, when added to a liquid, reduces its surface tension, thereby increasing its spreading and wetting properties.
What is Pluronic® F-68 used for?
Pluronic® F-68 can also be used to reduce foaming in stirred cultures and reduce cell attachment to glass. Pluronic® F-68 is provided at a concentration of 10% and effective at a working concentration of 0.1%.
What is Pluronic F68 used for in microbiology?
Gibco® Pluronic® F-68 is a non-ionic surfactant used to control shear forces in suspension cultures. Pluronic® F-68 can also be used to reduce foaming in stirred cultures and reduce cell attachment to glass.
What does pf68 mean?
Pluronic F68 is used in cell culture as a stabilizer of cell membranes protecting from membrane shearing and additionally acts as an anti-foaming agent.
Where is the F-68 made?
Gibco® Pluronic® F-68 is manufactured at a cGMP compliant facility, located in Grand Island, New York. The facility is registered with the FDA as a medical device manufacturer and is certified to ISO 13485 standards. For Research Use Only. Not for use in diagnostic procedures.
